Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1067998 | 0.84 | SMN1; SMN2 (0.46) | NPC1RAB9ASMN1; SMN2CYP2C9ALOX15 | |
| SCHEMBL27808415 | 0.75 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2CYP2C9ALOX15 | |
| SCHEMBL3673130 | 0.73 | CYP2C9 (0.49) | CYP2C9ALOX15HSD17B10HCRTR1HCRTR2 | |
| SCHEMBL3672690 | 0.72 | KMT2A (0.44) | NPC1RAB9ASMN1; SMN2CYP2C9ALOX15 | |
| SCHEMBL3669987 | 0.72 | ALDH1A1 (0.47) | NPC1RAB9ASMN1; SMN2KMT2AKDM4E | |
| SCHEMBL13726528 | 0.70 | MEN1 (0.72) | SMN1; SMN2CYP2C9ALOX15HSD17B10MEN1 | |
| SCHEMBL3671623 | 0.70 | CYP2C9 (0.46) | CYP2C9ALOX15HSD17B10MEN1KMT2A | |
| SCHEMBL3670794 | 0.70 | MAPK1 (0.51) | SMN1; SMN2ALOX15HSD17B10MEN1KMT2A | |
| SCHEMBL27808417 | 0.70 | CYP2C9 (0.51) | CYP2C9ALOX15HSD17B10HCRTR1HCRTR2 | |
| SCHEMBL5753998 | 0.68 | CYP2A13 (0.53) | NPC1RAB9ASMN1; SMN2CYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642296-B2 | 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-05 | — | — | US | disclosed |
| US-20070240609-A1 | Photoinitiators | IGM GROUP B.V. (NL) | 2007-10-18 | — | — | US | disclosed |