Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3678678 | 0.85 | TSHR (0.44) | TSHRSLC6A4ALDH1A1SLC6A2TAAR1 | |
| SCHEMBL3675441 | 0.83 | AOC3 (0.34) | TSHRSLC6A4SLC6A2TAAR1MAOA | |
| SCHEMBL3865062 | 0.77 | ESR1 (0.46) | TSHRSLC6A4MAOA | |
| SCHEMBL382196 | 0.77 | ESR1 (0.46) | TSHRSLC6A4MAOA | |
| SCHEMBL3863813 | 0.77 | ESR1 (0.46) | TSHRSLC6A4MAOA | |
| SCHEMBL4340700 | 0.77 | ALDH1A1 (0.48) | TSHRSLC6A4ALDH1A1 | |
| SCHEMBL3671138 | 0.77 | TSHR (0.39) | TSHRSLC6A4ALDH1A1SLC6A2TAAR1 | |
| SCHEMBL1729214 | 0.77 | MC4R (0.42) | ALDH1A1 | |
| SCHEMBL12261511 | 0.77 | MC4R (0.42) | ALDH1A1 | |
| SCHEMBL1728842 | 0.77 | MC4R (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1426392-B1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL CO (JP) | 2010-02-24 | — | — | EP | disclosed |
| US-6960640-B2 | Composition for optical material | MITSUBISHI GAS CHEMICAL CO., LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20040147708-A1 | Composition for optical material | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1426392-A1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-06-09 | — | — | EP | disclosed |