Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3678678 | 0.85 | TSHR (0.44) | ALDH1A1TSHRSLC6A4 | |
| SCHEMBL9439770 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CYP3A4ALOX15CASP1CASP7 | |
| SCHEMBL11776948 | 0.81 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TSHRSLC6A4TDP1 | |
| SCHEMBL1537231 | 0.79 | CYP1A2 (0.43) | ALDH1A1CYP3A4ALOX15CASP1CASP7 | |
| SCHEMBL1602038 | 0.79 | ALDH1A1 (0.45) | ALDH1A1CYP3A4ALOX15CASP1CASP7 | |
| SCHEMBL27342300 | 0.79 | ALOX15 (0.41) | ALDH1A1CYP3A4ALOX15CASP1CASP7 | |
| SCHEMBL2495978 | 0.79 | ALDH1A1 (0.45) | ALDH1A1CYP3A4ALOX15CASP1CASP7 | |
| SCHEMBL16805956 | 0.78 | TAAR1 (0.41) | ALDH1A1CYP3A4ALOX15CASP1CASP7 | |
| SCHEMBL9439895 | 0.78 | CYP1A2 (0.42) | ALDH1A1CYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL8127391 | 0.77 | HRH1 (0.43) | ALDH1A1CYP3A4ALOX15CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105916499-B | 12-epi-pleuromutilins | 纳布里瓦治疗股份公司 | 2020-02-18 | — | — | CN | disclosed |
| US-9481684-B2 | Gonadotropin releasing hormone receptor antagonists, method for the preparation thereof and pharmaceutical composition comprising the same | SK CHEMICALS CO., LTD. (KR) | 2016-11-01 | — | — | US | disclosed |
| US-20150166558-A1 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | SK CHEMICALS CO., LTD. (KR) | 2015-06-18 | — | — | US | disclosed |
| WO-2013129879-A1 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | SK CHEMICALS CO., LTD. (KR) | 2013-09-06 | — | — | WO | disclosed |
| US-8471290-B2 | Compositions and methods for generating white light | Rutgers. The State University of New Jersey (US) | 2013-06-25 | — | — | US | disclosed |
| US-20110049560-A1 | COMPOSITIONS AND METHODS FOR GENERATING WHITE LIGHT | NATIONAL SCIENCE FOUNDATION | 2011-03-03 | — | — | US | disclosed |
| WO-2009120716-A1 | COMPOSITIONS AND METHODS FOR GENERATING WHITE LIGHT | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2009-10-01 | — | — | WO | disclosed |
| EP-1020513-B1 | Laundry article which attracts soil and dyes | NAT STARCH CHEM INVEST (US) | 2002-12-11 | — | — | EP | disclosed |
| US-20020082425-A1 | For therapy of obesity and diabetes | NEUROGEN CORPORATION | 2002-06-27 | — | — | US | disclosed |
| US-6271241-B1 | BENZYLIMIDAZOLE DERIVATIVES AS MODULATORS OF BLOOD GLUCOSE LEVELS, ALSO USEFUL AS PROBES FOR LOCALIZATION OF CELLULAR RECEPTORS INVOLVED WITH SUCH MODULATION; FOOD METABOLISM AND FEEDING; TREATING DIABETES, OBESITY | NEUROGEN CORPORATION | 2001-08-07 | — | — | US | disclosed |
| US-6228783-B1 | ARTICLE EFFECTIVE FOR INHIBITING TRANSFER OF EXTRANEOUS DYES AND SOIL TO ARTICLES IN WASH LIQUOR | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION | 2001-05-08 | — | — | US | disclosed |
| EP-1020513-A2 | Laundry article which attracts soil and dyes | National Starch and Chemical Investment Holding Corporation (US) | 2000-07-19 | — | — | EP | disclosed |
| EP-0984056-A1 | Functionalized polyamines | National Starch and Chemical Investment Holding Corporation (US) | 2000-03-08 | — | — | EP | disclosed |
| US-6008316-A | Functionalized polyamines | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1999-12-28 | — | — | US | disclosed |
| US-5336749-A | Alicyclic diamines, alicyclic diisocyanates and polyisocyanato-isocyanurates and method for the preparation thereof | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-08-09 | — | — | US | disclosed |
| EP-0394058-B1 | ALICYCLIC DIAMINES, ALICYCLIC DIISOCYANATES AND POLYISOCYANATO-ISOCYANURATES AND METHOD FOR THE PREPARATION THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-08-25 | — | — | EP | disclosed |
| US-5210286-A | Hydrogenation of corresponding aromatic compound, reaction with phosgene | MITSUI TOATSU CHEMICALS, INC. (JP) | 1993-05-11 | — | — | US | disclosed |
| US-5126426-A | Catalytic hydrogenation of aromatic diamine | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-06-30 | — | — | US | disclosed |
| CN-1046522-A | Alicyclic diamine and vulcabond of alicyclic ring and polyisocyanate root close isocyanuric acid ester and preparation method thereof | MITSUI TOATSU CHEMICALS (JP) | 1990-10-31 | — | — | CN | disclosed |
| EP-0394058-A1 | Alicyclic diamines, alicyclic diisocyanates and polyisocyanato-isocyanurates and method for the preparation thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166558-A1 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | GNRHR, FSHR, GHRHR | ALDH1A1 4385/4885CYP3A4 3011/4885ALOX15 1060/4885 |
| US-20020082425-A1 | For therapy of obesity and diabetes | GPR119, GLP1R, NPY1R | ALDH1A1 363/4885CYP3A4 1082/4885ALOX15 1756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.