Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15052946 | 1.00 | LMNA (0.34) | LMNAMAPTMEN1MAPK1CASP2 | |
| Hydrochloric Acid SCHEMBL368041 | 1.00 | LMNA (0.34) | LMNAMAPTMEN1MAPK1CASP2 | |
| Hydrochloric Acid SCHEMBL2293581 | 1.00 | LMNA (0.34) | LMNAMAPTMEN1MAPK1CASP2 | |
| Hydrochloric Acid SCHEMBL367287 | 1.00 | LMNA (0.34) | LMNAMAPTMEN1MAPK1CASP2 | |
| SCHEMBL367893 | 0.98 | LMNA (0.35) | LMNAMAPTCYP2D6SPHK1GMNN | |
| Hydrochloric Acid SCHEMBL365179 | 0.98 | LMNA (0.31) | LMNA | |
| Iodide SCHEMBL15008381 | 0.97 | LMNA (0.34) | LMNAMAPTSMN1; SMN2CYP2D6SPHK1 | |
| Iodide SCHEMBL15008594 | 0.97 | LMNA (0.34) | LMNAMAPTSMN1; SMN2CYP2D6SPHK1 | |
| Iodide SCHEMBL15053220 | 0.97 | LMNA (0.34) | LMNAMAPTSMN1; SMN2CYP2D6SPHK1 | |
| Iodide SCHEMBL15008815 | 0.97 | LMNA (0.34) | LMNAMAPTSMN1; SMN2CYP2D6SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110185788-A1 | IONIC LIQUIDS AS SOLVENTS IN HEADSPACE GAS CHROMATOGRAPHY | KOCH PETER | 2011-08-04 | — | — | US | claimed |
| US-20100239524-A1 | MICROPARTICLES PREPARED USING AN IONIC LIQUID | NOVARTIS AG (CH) | 2010-09-23 | — | — | US | claimed |
| US-7569149-B2 | Ionic liquids as solvents in headspace gas chromatography | NOVARTIS AG (CH) | 2009-08-04 | — | — | US | claimed |
| US-20050205493-A1 | Ionic liquids as solvents in headspace gas chromatography | NOVARTIS AG (CH) | 2005-09-22 | — | — | US | claimed |
| US-5994602-A | IN THE PRESENCE OF A HYDROCARBYL ALUMINUM OR GALLIUM HALIDE AND A HYDROCARBYL-SUBSTITUTED IMIDAZOLIUM OR PYRIDINIUM HALIDE | BP CHEMICALS LIMITED (GB) | 1999-11-30 | — | — | US | claimed |
| EP-0693045-B1 | ALKYLATION PROCESS | BP CHEM INT LTD (GB) | 1997-10-22 | — | — | EP | claimed |
| EP-0693045-A1 | ALKYLATION PROCESS | BP CHEM INT LTD (GB) | 1996-01-24 | — | — | EP | claimed |
| WO-1995021872-A1 | IONIC LIQUIDS | BP CHEMICALS LIMITED (GB) | 1995-08-17 | — | — | WO | claimed |
| WO-1995021806-A1 | ALKYLATION PROCESS | BP CHEMICALS LIMITED (GB) | 1995-08-17 | — | — | WO | claimed |
| EP-2593403-B1 | METHOD FOR PRODUCING A GEL FILM AND FILTRATION MEMBRANE PREPARED WITH THIS METHOD | UNIV MONASH (AU) | 2020-03-04 | — | — | EP | disclosed |
| US-10297396-B2 | Graphene-based films | MONASH UNIVERSITY (AU) | 2019-05-21 | — | — | US | disclosed |
| EP-2615632-B1 | MICROSTRUCTURE MANUFACTURING METHOD USING TREATMENT LIQUID FOR INHIBITING PATTERN COLLAPSE IN MICROSTRUCTURES | MITSUBISHI GAS CHEMICAL CO (JP) | 2019-05-08 | — | — | EP | disclosed |
| US-9751763-B2 | Material and applications therefor | MONASH UNIVERSITY (AU) | 2017-09-05 | — | — | US | disclosed |
| US-20160016804-A1 | GRAPHENE-BASED FILMS | MONASH UNIVERSITY (AU) | 2016-01-21 | — | — | US | disclosed |
| WO-2000041809-A1 | IONIC LIQUID CATALYST FOR ALKYLATION | BP CHEMICALS LIMITED (GB) | 2000-07-20 | — | — | WO | disclosed |
| US-5994602-A | IN THE PRESENCE OF A HYDROCARBYL ALUMINUM OR GALLIUM HALIDE AND A HYDROCARBYL-SUBSTITUTED IMIDAZOLIUM OR PYRIDINIUM HALIDE | BP CHEMICALS LIMITED (GB) | 1999-11-30 | — | — | US | disclosed |
| EP-0693045-B1 | ALKYLATION PROCESS | BP CHEM INT LTD (GB) | 1997-10-22 | — | — | EP | disclosed |
| EP-0693045-A1 | ALKYLATION PROCESS | BP CHEM INT LTD (GB) | 1996-01-24 | — | — | EP | disclosed |
| WO-1995021806-A1 | ALKYLATION PROCESS | BP CHEMICALS LIMITED (GB) | 1995-08-17 | — | — | WO | disclosed |
| WO-1995021872-A1 | IONIC LIQUIDS | BP CHEMICALS LIMITED (GB) | 1995-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100239524-A1 | MICROPARTICLES PREPARED USING AN IONIC LIQUID | FIBP, MIF, CHMP4B | LMNA 142/4885MAPT 1567/4885MEN1 1303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.