Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PYCR1 | P32322 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3671198 | 0.96 | LMNA (0.37) | EPHX2PYCR1LMNANR1H4MLYCD | |
| SCHEMBL3669475 | 0.82 | ACE2 (0.43) | EPHX2LMNANR1H4MLYCDALDH1A1 | |
| SCHEMBL3742558 | 0.79 | S1PR1 (0.40) | EPHX2LMNANR1H4ALDH1A1MAPT | |
| SCHEMBL3671777 | 0.79 | ALDH1A1 (0.46) | MLYCDCA2ALDH1A1POLBMAPT | |
| SCHEMBL3675015 | 0.77 | S1PR1 (0.39) | EPHX2NR1H4MLYCDCA2MAOB | |
| SCHEMBL7640361 | 0.76 | SMN1; SMN2 (0.50) | LMNANR1H4ALDH1A1POLBMAPT | |
| SCHEMBL3676655 | 0.75 | ALDH1A1 (0.43) | CA2ALDH1A1POLBMAPTCYP1A2 | |
| SCHEMBL3672416 | 0.75 | MRGPRX4 (0.38) | EPHX2LMNANR1H4ALDH1A1MAPT | |
| SCHEMBL3673792 | 0.74 | ALDH1A1 (0.42) | CA2ALDH1A1POLBMAPTCYP1A2 | |
| SCHEMBL24401195 | 0.73 | POLB (0.49) | PYCR1LMNAALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642296-B2 | 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-05 | — | — | US | disclosed |
| US-20070240609-A1 | Photoinitiators | IGM GROUP B.V. (NL) | 2007-10-18 | — | — | US | disclosed |
| EP-1763499-B1 | NEW PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2007-09-26 | — | — | EP | disclosed |