Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 11/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 8/20 | 0.47 |
| ▸ | TUBB | P07437 | 8/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 8/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 8/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3673307 | 1.00 | MAPT (0.47) | MAPTLMNAKMT2AMEN1ATM | |
| SCHEMBL4256028 | 0.92 | MAPT (0.52) | MAPTLMNAKMT2AMEN1ATM | |
| SCHEMBL4256030 | 0.92 | MAPT (0.52) | MAPTLMNAKMT2AMEN1ATM | |
| SCHEMBL4264700 | 0.88 | MAPT (0.49) | MAPTLMNAKMT2AMEN1ATM | |
| SCHEMBL4264707 | 0.88 | MAPT (0.49) | MAPTLMNAKMT2AMEN1ATM | |
| SCHEMBL4264098 | 0.86 | TUBB1 (0.51) | MAPTLMNAKMT2AMEN1ATM | |
| SCHEMBL4264100 | 0.86 | TUBB1 (0.51) | MAPTLMNAKMT2AMEN1ATM | |
| SCHEMBL4259583 | 0.84 | TNFRSF1A (0.57) | MAPTLMNAKMT2AMEN1TUBB1 | |
| SCHEMBL4259579 | 0.84 | TNFRSF1A (0.57) | MAPTLMNAKMT2AMEN1TUBB1 | |
| SCHEMBL3670547 | 0.82 | ALOX5 (0.49) | MAPTLMNAKMT2AMEN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4425628-B2 | — | — | 2010-03-03 | — | — | JP | claimed |
| EP-1435894-A4 | CYTOPROTECTIVE COMPOUNDS, PHARMACEUTICAL AND COSMETIC FORMULATIONS, AND METHODS | GALILEO PHARMACEUTICALS INC (US) | 2005-07-06 | — | — | EP | claimed |
| JP-2005505519-A | — | — | 2005-02-24 | — | — | JP | claimed |
| EP-1435894-A2 | CYTOPROTECTIVE COMPOUNDS, PHARMACEUTICAL AND COSMETIC FORMULATIONS, AND METHODS | Galileo Pharmaceuticals, Inc. (US) | 2004-07-14 | — | — | EP | claimed |
| US-20030073712-A1 | Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. | 2003-04-17 | — | — | US | claimed |
| WO-2003009807-A2 | CYTOPROTECTIVE COMPOUNDS, PHARMACEUTICAL AND COSMETIC FORMULATIONS, AND METHODS | GALILEO LABORATORIES, INC. (US) | 2003-02-06 | — | — | WO | claimed |
| US-7629375-B2 | Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2009-12-08 | — | — | US | disclosed |
| US-20060178356-A1 | Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods | GALILEO PHARMACEUTICALS, INC. | 2006-08-10 | — | — | US | disclosed |
| EP-1435894-A4 | CYTOPROTECTIVE COMPOUNDS, PHARMACEUTICAL AND COSMETIC FORMULATIONS, AND METHODS | GALILEO PHARMACEUTICALS INC (US) | 2005-07-06 | — | — | EP | disclosed |
| US-20050142155-A1 | Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods | JOHNSON & JOHNSON CONSUMER INC. | 2005-06-30 | — | — | US | disclosed |
| US-20050113416-A1 | Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods | GALILEO PHARMACEUTICALS, INC. | 2005-05-26 | — | — | US | disclosed |
| EP-1435894-A2 | CYTOPROTECTIVE COMPOUNDS, PHARMACEUTICAL AND COSMETIC FORMULATIONS, AND METHODS | Galileo Pharmaceuticals, Inc. (US) | 2004-07-14 | — | — | EP | disclosed |
| US-20030073712-A1 | Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. | 2003-04-17 | — | — | US | disclosed |
| WO-2003009807-A2 | CYTOPROTECTIVE COMPOUNDS, PHARMACEUTICAL AND COSMETIC FORMULATIONS, AND METHODS | GALILEO LABORATORIES, INC. (US) | 2003-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050142155-A1 | Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods | HSF1, HMOX1, NQO1 | MAPT 2548/4885LMNA 900/4885KMT2A 4665/4885 |
| US-20030073712-A1 | Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods | HSF1, HMOX1, NQO1 | MAPT 2548/4885LMNA 900/4885KMT2A 4665/4885 |
| US-20050113416-A1 | Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods | HSF1, HMOX1, NQO1 | MAPT 2548/4885LMNA 900/4885KMT2A 4665/4885 |
| US-20060178356-A1 | Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods | HSF1, HMOX1, NQO1 | MAPT 2548/4885LMNA 900/4885KMT2A 4665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.