Sugi Predict

Sugi Predict / Compounds / Formic Acid

Formic Acid

Formic Acid

SCHEMBL3673358

O=CO.O=S(=O)(c1cccc2c1OCC2)n1ccc2c(N3CCNCC3)cccc21

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ HTR6 P50406 20/20 0.59
▸ HTR1A P08908 1/20 0.43
▸ DRD2 P14416 1/20 0.43
▸ HTR2A P28223 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5008967 0.95 HTR6 (0.64) HTR6HTR1ADRD2HTR2A
Formic Acid SCHEMBL3673523 0.85 HTR6 (0.59) HTR6HTR1ADRD2HTR2A
Formic Acid SCHEMBL3678413 0.82 HTR6 (0.59) HTR6HTR1ADRD2HTR2A
SCHEMBL12519880 0.81 HTR6 (0.63) HTR6HTR1ADRD2HTR2A
SCHEMBL5005907 0.80 HTR6 (0.64) HTR6HTR1ADRD2HTR2A
SCHEMBL3673360 0.78 HTR6 (0.46) HTR6
SCHEMBL5008974 0.76 HTR6 (0.64) HTR6HTR1ADRD2HTR2A
SCHEMBL5010931 0.76 HTR6 (0.64) HTR6HTR1ADRD2HTR2A
Hydrochloric Acid SCHEMBL4309981 0.76 HTR6 (0.77) HTR6HTR1ADRD2HTR2A
SCHEMBL3680522 0.76 HTR6 (0.61) HTR6HTR1ADRD2HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2162433-A2 4' SUBSTITUTED COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY Memory Pharmaceuticals Corporation (US) 2010-03-17 — — EP disclosed
WO-2008147812-A2 4' SUBSTITUTED COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY MEMORY PHARMACEUTICALS CORPORATION (US) 2008-12-04 — — WO disclosed