Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010931 | 0.95 | HTR6 (0.64) | HTR6HTR1ADRD2HTR2A | |
| SCHEMBL5008974 | 0.88 | HTR6 (0.64) | HTR6HTR1ADRD2HTR2A | |
| Formic Acid SCHEMBL3673523 | 0.82 | HTR6 (0.59) | HTR6HTR1ADRD2HTR2A | |
| Formic Acid SCHEMBL3673358 | 0.82 | HTR6 (0.59) | HTR6HTR1ADRD2HTR2A | |
| SCHEMBL3640843 | 0.81 | HTR6 (0.63) | HTR6HTR1ADRD2HTR2A | |
| SCHEMBL3644217 | 0.79 | HTR6 (0.62) | HTR6HTR1ADRD2HTR2A | |
| SCHEMBL3678416 | 0.78 | HTR6 (0.49) | HTR6 | |
| SCHEMBL14359363 | 0.77 | HTR6 (0.77) | HTR6HTR1ADRD2HTR2A | |
| SCHEMBL3672099 | 0.76 | HTR6 (0.61) | HTR6HTR1ADRD2HTR2A | |
| SCHEMBL5009048 | 0.76 | HTR6 (0.61) | HTR6HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162433-A2 | 4' SUBSTITUTED COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | Memory Pharmaceuticals Corporation (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008147812-A2 | 4' SUBSTITUTED COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2008-12-04 | — | — | WO | disclosed |