SCHEMBL367337

SCHEMBL367337

C=CC(=O)OCCC(=C)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.54
ALDH1A1 P00352 4/20 0.54
TP53 P04637 3/20 0.54
HIF1A Q16665 3/20 0.54
HSD17B10 Q99714 2/20 0.54
CYP3A4 P08684 2/20 0.54
HPGD P15428 1/20 0.48
THRB P10828 2/20 0.44
ALOX15 P16050 1/20 0.42
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HCAR2 Q8TDS4 1/20 0.31
LMNA P02545 1/20 0.31
TET2 Q6N021 3/20 0.30
TET3 O43151 1/20 0.30
TET1 Q8NFU7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30130368 0.89 TSHR (0.48) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL29919951 0.89 TSHR (0.47) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL2781456 0.88 TSHR (0.61) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL29842172 0.86 TSHR (0.48) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL1169261 0.85 TSHR (0.68) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL29849704 0.84 TSHR (0.43) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL29425574 0.83 TSHR (0.55) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL30540301 0.83 TSHR (0.46) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL4606582 0.82 TSHR (0.63) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL11029235 0.82 TSHR (0.53) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110670359-B Low-temperature type waterproof and oil-proof agent and preparation method thereof 广东中联邦精细化工有限公司 2022-02-11 CN claimed
CN-110670359-A Low-temperature type waterproof and oil-proof agent and preparation method thereof 广东中联邦精细化工有限公司 2020-01-10 CN claimed
CN-110670359-B Low-temperature type waterproof and oil-proof agent and preparation method thereof 广东中联邦精细化工有限公司 2022-02-11 CN disclosed
CN-113943504-A Active energy ray-curable coating agent, cured product, and laminate 荒川化学工业株式会社 2022-01-18 CN disclosed
CN-110670359-A Low-temperature type waterproof and oil-proof agent and preparation method thereof 广东中联邦精细化工有限公司 2020-01-10 CN disclosed
EP-2406239-B1 CYCLIC CARBAMATE COMPOUNDS USEFUL IN ENERGY-CURABLE COMPOSITIONS SUN CHEMICAL BV (NL) 2016-09-14 EP disclosed
US-9428471-B2 Cyclic carbamate compounds useful in energy-curable compositions SUN CHEMICAL B.V. (NL) 2016-08-30 US disclosed
US-20120015159-A1 CYCLIC CARBAMATE COMPOUNDS USEFUL IN ENERGY-CURABLE COMPOSITIONS SUN CHEMICAL B.V. (NL) 2012-01-19 US disclosed
EP-2406239-A1 CYCLIC CARBAMATE COMPOUNDS USEFUL IN ENERGY-CURABLE COMPOSITIONS Sun Chemical B.V. (NL) 2012-01-18 EP disclosed
WO-2010103281-A1 CYCLIC CARBAMATE COMPOUNDS USEFUL IN ENERGY-CURABLE COMPOSITIONS SUN CHEMICAL B.V. (NL) 2010-09-16 WO disclosed
US-20100099590-A1 Oil dispersible polymer nanoparticles QUEEN'S UNIVERSITY AT KINGSTON (CA) 2010-04-22 US disclosed
WO-2007068102-A2 OIL DISPERSIBLE POLYMER NANOPARTICLES QUEEN'S UNIVERSITY AT KINGSTON (CA) 2007-06-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120015159-A1 CYCLIC CARBAMATE COMPOUNDS USEFUL IN ENERGY-CURABLE COMPOSITIONS ACMSD, PYCARD, DNMT3L TSHR 4427/4885ALDH1A1 1459/4885TP53 1557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.