O-Xylene

O-Xylene

SCHEMBL3673577

C=CC.Cc1ccccc1C

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.67
ACHE P22303 3/20 0.67
ALDH1A1 P00352 5/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA7 P43166 2/20 0.43
CA9 Q16790 2/20 0.43
TDP1 Q9NUW8 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP1A2 P05177 2/20 0.40
CYP2A6 P11509 2/20 0.40
LMNA P02545 1/20 0.37
ALOX12 P18054 1/20 0.37
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36
ESR1 P03372 1/20 0.36
TAAR1 Q96RJ0 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL16892914 0.97 TSHR (0.62) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL16048907 0.97 TSHR (0.62) TSHRACHEALDH1A1CA1CA2
P-Xylene SCHEMBL11590506 0.91 ACHE (0.56) TSHRACHEALDH1A1CA1CA2
P-Xylene SCHEMBL11664570 0.89 ACHE (0.53) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL7624343 0.87 TSHR (0.67) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL8642954 0.84 TSHR (0.62) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL9421590 0.82 TSHR (0.83) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL8216257 0.82 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL10522915 0.82 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL772 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117855413-A Preparation method of gradient filling multi-level carbon-coated silicon-carbon composite material 中国石油大学(华东) 2024-04-09 CN claimed
EP-4106722-A1 PRESSURISED METERED DOSE INHALERS COMPRISING A BUFFERED PHARMACEUTICAL FORMULATION Chiesi Farmaceutici S.p.A. (IT) 2022-12-28 EP claimed
WO-2013103699-A1 DRILL BIT AND CHUCK ISOLATORS CORRY RUBBER CORPORATION (US) 2013-07-11 WO claimed
EP-0400333-B1 Plasto-elastic polypropylene compositions MONTELL NORTH AMERICA INC (US) 1995-11-08 EP claimed
EP-4373898-A1 ACRYLATE ADHESIVE FOR CONTACT WITH LIQUID COOLANT Zephyros Inc. (US) 2024-05-29 EP disclosed
CN-117855413-A Preparation method of gradient filling multi-level carbon-coated silicon-carbon composite material 中国石油大学(华东) 2024-04-09 CN disclosed
WO-2023001806-A1 ACRYLATE ADHESIVE FOR CONTACT WITH LIQUID COOLANT ZEPHYROS, INC. (US) 2023-01-26 WO disclosed
EP-4118169-A1 OIL-BASED CORROSION INHIBITORS The Lubrizol Corporation (US) 2023-01-18 EP disclosed
EP-4106722-A1 PRESSURISED METERED DOSE INHALERS COMPRISING A BUFFERED PHARMACEUTICAL FORMULATION Chiesi Farmaceutici S.p.A. (IT) 2022-12-28 EP disclosed
WO-2022132417-A1 LAMINATED STRUCTURES WITH ADHESIVE POLYMERIC INTERLAYER COMPRISING COHESIVE DEBONDING ZONES FOR ENHANCED PERFORMANCE KURARAY EUROPE GMBH (DE) 2022-06-23 WO disclosed
WO-2021183230-A1 OIL-BASED CORROSION INHIBITORS THE LUBRIZOL CORPORATION (US) 2021-09-16 WO disclosed
US-10407518-B2 Catalyst support and related processes BRASKEM S.A. (BR) 2019-09-10 US disclosed
US-4952737-A MAGNESIUM CHLORIDE ADDUCT WITH ALCOHOL AND PHENOL USED TO PREPARE COORDINATION CATALYST PHILLIPS PETROLEUM COMPANY (US) 1990-08-28 US disclosed
EP-0299486-A2 Propylene polymer composition SHOWA DENKO KABUSHIKI KAISHA (JP) 1989-01-18 EP disclosed
US-4559317-A COORDINATION CATALYSTS COMPRISING FLUOROALKYL MAGNESIUM OXIDE, TITANIUM HALIDE AND ALUMINUM COMPOUND PHILLIPS PETROLEUM COMPANY (US) 1985-12-17 US disclosed
US-4549001-A COORDINATION CATALYST OF FLUORINATED MAGNESIUM ALKOXIDE TETRAVALENT HALOGENATED TITANIUM AND ORGANO-ALUMINUM COMPOUND PHILLIPS PETROLEUM COMPANY (US) 1985-10-22 US disclosed
US-4469908-A LIQUID PHASE, ZEOLITE ZSM-12 MOBIL OIL CORPORATION (US) 1984-09-04 US disclosed
EP-0085710-A4 RUBBER COMPOSITIONS. RUBBER RES ELASTOMERICS INC (US) 1983-12-23 EP disclosed
EP-0085710-A1 RUBBER COMPOSITIONS. RUBBER RES ELASTOMERICS (US) 1983-08-17 EP disclosed
WO-1983000489-A1 RUBBER COMPOSITIONS RUBBER RES ELASTOMERICS (US) 1983-02-17 WO disclosed