Biphenyl

Biphenyl

SCHEMBL3673774

C=C[SiH2]OCC.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 4/20 0.36
TSHR P16473 1/20 0.34
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
RELA Q04206 1/20 0.32
DHODH Q02127 1/20 0.32
HPGD P15428 2/20 0.32
KDM4E B2RXH2 1/20 0.32
TP53 P04637 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL282677 0.80
Biphenyl SCHEMBL34936 0.76 ALDH1A1 (0.45) ALDH1A1NPC1RAB9AL3MBTL1SMN1; SMN2
Biphenyl SCHEMBL27419458 0.74 ALDH1A1 (0.43) ALDH1A1NPC1RAB9AL3MBTL1SMN1; SMN2
Biphenyl SCHEMBL8087057 0.74 ALDH1A1 (0.43) NPSR1ALDH1A1NPC1RAB9AL3MBTL1
Biphenyl SCHEMBL896273 0.72 ALDH1A1 (0.41) ALDH1A1NPC1RAB9AL3MBTL1SMN1; SMN2
Biphenyl SCHEMBL3301393 0.71 ALDH1A1 (0.39) ALDH1A1NPC1RAB9AL3MBTL1SMN1; SMN2
SCHEMBL676431 0.71 TSHR (0.46) ALDH1A1TSHRL3MBTL1MAPTMAPK1
Biphenyl SCHEMBL8734478 0.71 ALDH1A1 (0.50) ALDH1A1TSHRL3MBTL1SMN1; SMN2MAPT
Ether SCHEMBL28657814 0.71 ALDH1A1 (0.48) ALDH1A1TSHRNPC1RAB9AL3MBTL1
Diethylamine SCHEMBL28798180 0.70 TP53 (0.38) TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100271699-A1 COATING COMPOSITION FOR ANTIREFLECTION AND ANTIREFLECTION FILM PREPARED BY USING THE SAME LG CHEM, LTD. (KR) 2010-10-28 US disclosed
EP-0288209-A1 Polyimide resin compositions MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-10-26 EP disclosed