SCHEMBL3673839

SCHEMBL3673839

FC(F)(F)C(c1cccc(I)c1)(c1cccc(I)c1)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
TSHR P16473 2/20 0.35
MAPK1 P28482 1/20 0.35
PGK1 P00558 1/20 0.33
PGK2 P07205 1/20 0.33
ALDH1A1 P00352 1/20 0.33
IDO1 P14902 2/20 0.32
MGLL Q99685 2/20 0.32
CES2 O00748 1/20 0.32
FAAH O00519 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28028711 0.82 TSHR (0.35) TSHRMAPK1PGK1PGK2ALDH1A1
SCHEMBL1377 0.81 TSHR (0.54) TSHRMAPK1ALDH1A1IDO1MGLL
SCHEMBL29438862 0.81 TSHR (0.54) TSHRMAPK1ALDH1A1IDO1MGLL
SCHEMBL15191919 0.78 PDE2A (0.37) ESR1ESR2TSHRMAPK1PGK1
SCHEMBL23240898 0.77 TSHR (0.40) TSHRMAPK1PGK1PGK2ALDH1A1
SCHEMBL30148546 0.77 TAS1R3 (0.37) ESR1ESR2TSHRMAPK1PGK1
SCHEMBL5240704 0.77 TSHR (0.35) TSHRMAPK1PGK1PGK2ALDH1A1
SCHEMBL22619018 0.77 PGK1 (0.38) TSHRMAPK1PGK1PGK2ALDH1A1
SCHEMBL6899596 0.77 TAS1R3 (0.37) ESR1ESR2TSHRMAPK1PGK1
SCHEMBL8999922 0.76 TSHR (0.54) TSHRMAPK1ALDH1A1IDO1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1329444-B1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2010-05-05 EP disclosed
US-6933068-B2 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2005-08-23 US disclosed
EP-1245554-B1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR CORP (JP) 2005-01-26 EP disclosed
US-6833426-B2 A proton-conductive membrane containing the sulfonic acid group-containing polyarylene (co)polymer JSR CORPORATION (JP) 2004-12-21 US disclosed
US-6794480-B2 POLYARYLENE-BASED COPOLYMER USEFUL AS PROTON-CONDUCTIVE MEMBRANE WHICH CAN BE USED AS ELECTRON FOR PRIMARY BATTERY, ELECTROLYTE FOR SECONDARY BATTERY, HIGH MOLECULAR SOLID ELECTROLYTE FOR FUEL CELL JSR CORPORATION (JP) 2004-09-21 US disclosed
US-20030173547-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORPORATION (JP) 2003-09-18 US disclosed
EP-1329444-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2003-07-23 EP disclosed
US-20020177656-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR CORPORATION (JP) 2002-11-28 US disclosed
US-20020172850-A1 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION 2002-11-21 US disclosed
EP-1245554-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR Corporation (JP) 2002-10-02 EP disclosed
US-5578697-A DIELECTRIC POLYMERS FOR ELECTRONICS KABUSHIKI KAISHA TOSHIBA (JP) 1996-11-26 US disclosed