SCHEMBL3673845

SCHEMBL3673845

COC(=O)OC1C/C=C(/C)CCCC1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.37
POLB P06746 2/20 0.34
ALDH1A1 P00352 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
CASP6 P55212 1/20 0.34
CTDSP1 Q9GZU7 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
NPC1 O15118 1/20 0.34
TSHR P16473 1/20 0.34
RAB9A P51151 1/20 0.34
LMNA P02545 3/20 0.33
USP2 O75604 1/20 0.33
CYP19A1 P11511 1/20 0.33
EPHX1 P07099 1/20 0.33
KDM4E B2RXH2 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ACACB O00763 1/20 0.32
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3673848 1.00 PTPN1 (0.37) PTPN1POLBALDH1A1SMN1; SMN2CASP6
SCHEMBL9723379 0.89 LMNA (0.40) PTPN1POLBALDH1A1SMN1; SMN2CASP6
SCHEMBL3670092 0.84 TAS2R46 (0.40) POLBALDH1A1SMN1; SMN2CASP6CTDSP1
SCHEMBL3670091 0.84 TAS2R46 (0.40) POLBALDH1A1SMN1; SMN2CASP6CTDSP1
SCHEMBL3675544 0.83 PTPN1 (0.38) PTPN1POLBSMN1; SMN2NPC1TSHR
SCHEMBL3675543 0.83 PTPN1 (0.38) PTPN1POLBSMN1; SMN2NPC1TSHR
SCHEMBL3674665 0.79 PTPN1 (0.38) PTPN1POLBALDH1A1SMN1; SMN2NPC1
SCHEMBL3674667 0.79 PTPN1 (0.38) PTPN1POLBALDH1A1SMN1; SMN2NPC1
SCHEMBL3678220 0.78 PTPN1 (0.34) PTPN1POLBALDH1A1SMN1; SMN2CASP6
SCHEMBL3678222 0.78 PTPN1 (0.34) PTPN1POLBALDH1A1SMN1; SMN2CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7723423-B2 Gas-barrier resin composition CRYOVAC, INC. (US) 2010-05-25 US disclosed
EP-1746131-B1 Gas-barrier resin composition CRYOVAC INC (US) 2009-01-21 EP disclosed
US-7285598-B2 Polymer and process for producing the same KURARAY CO., LTD. (JP) 2007-10-23 US disclosed
US-20070093599-A1 Gas-barrier resin composition CRYOVAC, INC. (US) 2007-04-26 US disclosed
US-20070021556-A1 Gas-barrier resin composition KURARAY CO. LTD. (JP) 2007-01-25 US disclosed
EP-1746131-A2 Gas-barrier resin composition Cryovac, Inc. (US) 2007-01-24 EP disclosed
US-20060149009-A1 Produced by ring-opening, in the presence of a metal alkylidene complex comprising a ligand with an imidazolidine structure, a cyclic olefin comprising at least one cyclic olefin further comprising a hydroxy group or a functional group that can be converted into a hydroxy group, and hydrogenating KURARAY CO., LTD. (JP) 2006-07-06 US disclosed
EP-1598384-A1 NOVEL POLYMER AND PROCESS FOR PRODUCING THE SAME KURARAY CO., LTD. (JP) 2005-11-23 EP disclosed