SCHEMBL3673890

SCHEMBL3673890

COCC(=O)NC(C)C(=O)OC

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
RECQL P46063 2/20 0.50
CA14 Q9ULX7 1/20 0.43
MAPT P10636 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 1/20 0.41
BIRC2 Q13490 1/20 0.41
NPSR1 Q6W5P4 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ACACB O00763 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3673892 1.00 TSHR (0.50) TSHRMEN1KMT2ARECQLCA14
SCHEMBL28127289 1.00 TSHR (0.50) TSHRMEN1KMT2ARECQLCA14
SCHEMBL9954665 0.85 TSHR (0.44) TSHRMEN1KMT2ARECQLCA14
SCHEMBL5128332 0.85 TSHR (0.44) TSHRMEN1KMT2ARECQLCA14
SCHEMBL2294079 0.83 SMN1; SMN2 (0.51) TSHRMAPTSMN1; SMN2ALDH1A1HPGD
SCHEMBL25646522 0.83 TSHR (0.46) TSHRMEN1KMT2ARECQLSMN1; SMN2
SCHEMBL2294082 0.83 SMN1; SMN2 (0.51) TSHRMAPTSMN1; SMN2ALDH1A1HPGD
SCHEMBL3397754 0.83 SMN1; SMN2 (0.51) TSHRMAPTSMN1; SMN2ALDH1A1HPGD
SCHEMBL13236365 0.80 RECQL (0.46) TSHRMEN1KMT2ARECQLCA14
SCHEMBL10272433 0.80 TSHR (0.51) TSHRMEN1KMT2ARECQLCA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11274083-B2 Substituted thiophenyl uracils, salts thereof and the use thereof as herbicidal agents SYNGENTA CROP PROTECTION AG (CH) 2022-03-15 US disclosed
EP-3728235-B1 SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2022-02-09 EP disclosed
US-20210087151-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2021-03-25 US disclosed
EP-2162000-A1 METHODS AND COMPOSITIONS COMPRISING HIGH VALENCY SILVER FOR INCREASING SEED GERMINATION Innovotech Inc. (CA) 2010-03-17 EP disclosed
WO-2008148221-A1 METHODS AND COMPOSITIONS COMPRISING HIGH VALENCY SILVER FOR INCREASING SEED GERMINATION INNOVOTECH INC. (CA) 2008-12-11 WO disclosed
EP-1009838-A2 METHOD FOR PROTECTING PLANTS Novartis AG (CH) 2000-06-21 EP disclosed
WO-1998029537-A2 METHOD FOR PROTECTING PLANTS NOVARTIS AG (CH) 1998-07-09 WO disclosed
EP-0537957-B1 Fungicidal silicon-containing compounds, their preparation and their agrochemical and medicinal uses SANKYO CO (JP) 1997-02-12 EP disclosed
EP-0431968-B1 Oxetane derivatives, their preparation and their use as anti-fungal or fungicidal agents SANKYO CO (JP) 1995-03-15 EP disclosed
EP-0332387-B1 Triazole derivatives, their preparation and their use as fungicides SANKYO CO (JP) 1993-11-24 EP disclosed
EP-0537957-A1 Fungicidal silicon-containing compounds, their preparation and their agrochemical and medicinal uses Sankyo Company Limited (JP) 1993-04-21 EP disclosed
EP-0350946-A2 Amide derivatives, and their production and agricultural and horticultural fungicides containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-01-17 EP disclosed
EP-0292937-A1 Amide derivatives, and their production and agricultural fungicides containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-11-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11274083-B2 Substituted thiophenyl uracils, salts thereof and the use thereof as herbicidal agents UNG, TYMP, TYMS TSHR 901/4885MEN1 4799/4885KMT2A 2855/4885
US-20210087151-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS UNG, TYMP, TYMS TSHR 901/4885MEN1 4799/4885KMT2A 2855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.