Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | LPL | P06858 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL429070 | 0.98 | CYP2A6 (0.48) | CYP2A6LPLLIPGESR1ESR2 | |
| SCHEMBL429952 | 0.98 | CYP2A6 (0.48) | CYP2A6LPLLIPGESR1ESR2 | |
| SCHEMBL2472869 | 0.98 | CYP2A6 (0.48) | CYP2A6LPLLIPGESR1ESR2 | |
| SCHEMBL19152839 | 0.91 | CYP2A6 (0.44) | CYP2A6LPLLIPGESR1ESR2 | |
| SCHEMBL20938291 | 0.91 | CYP11B1 (0.42) | CYP2A6LPLLIPGESR1ESR2 | |
| SCHEMBL25770839 | 0.89 | CYP2A6 (0.42) | CYP2A6LPLLIPGESR1ESR2 | |
| SCHEMBL431640 | 0.88 | CYP2A6 (0.43) | CYP2A6LPLLIPGCYP11B1CYP11B2 | |
| SCHEMBL322802 | 0.88 | CYP2A6 (0.43) | CYP2A6LPLLIPGCYP11B1CYP11B2 | |
| SCHEMBL431820 | 0.87 | MAPK1 (0.47) | PDK2SMN1; SMN2 | |
| SCHEMBL429037 | 0.87 | MAPK1 (0.47) | PDK2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415752-B1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME | IDEMITSU KOSAN CO (JP) | 2016-03-09 | — | — | EP | disclosed |
| US-9184395-B2 | Aromatic amine derivative and organic electroluminescent element using same | IDEMITSU KOSAN CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |
| US-9184395-B2 | Aromatic amine derivative and organic electroluminescent element using same | IDEMITSU KOSAN CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |
| US-8980442-B2 | Aromatic amine derivative and organic electroluminescent element using same | MITSUI CHEMICALS, INC. (JP) | 2015-03-17 | — | — | US | disclosed |
| CN-102356060-A | Aromatic amine derivative and organic electroluminescent element using same | MITSUI CHEMICALS INC | 2012-02-15 | — | — | CN | disclosed |
| EP-2415752-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME | Mitsui Chemicals, Inc. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20120012832-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME | MITSUI CHEMICALS, INC. (JP) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120012832-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME | MAOA, MAOB, TYR | CYP2A6 772/4885LPL 1699/4885LIPG 1996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.