SCHEMBL429070

SCHEMBL429070

CC1(C)c2cc(Br)ccc2-c2ccc(-c3ccc4c(c3)C(C)(C)c3cc(-c5ccc6cc(-c7ccc8ccccc8c7)ccc6c5)ccc3-4)cc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.48
LPL P06858 1/20 0.41
LIPG Q9Y5X9 1/20 0.41
CYP11B1 P15538 2/20 0.40
CYP11B2 P19099 2/20 0.40
GSTP1 P09211 1/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
PDK2 Q15119 1/20 0.39
ALOX5 P09917 1/20 0.39
HSD17B1 P14061 1/20 0.38
HSD17B2 P37059 1/20 0.38
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
PTGER3 P43115 2/20 0.36
CYP1A2 P05177 3/20 0.36
CYP17A1 P05093 1/20 0.36
CYP19A1 P11511 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2472869 1.00 CYP2A6 (0.48) CYP2A6LPLLIPGCYP11B1CYP11B2
SCHEMBL429952 1.00 CYP2A6 (0.48) CYP2A6LPLLIPGCYP11B1CYP11B2
SCHEMBL367400 0.98 CYP2A6 (0.47) CYP2A6LPLLIPGCYP11B1CYP11B2
SCHEMBL19152839 0.93 CYP2A6 (0.44) CYP2A6LPLLIPGCYP11B1CYP11B2
SCHEMBL20938291 0.92 CYP11B1 (0.42) CYP2A6LPLLIPGCYP11B1CYP11B2
SCHEMBL25770839 0.90 CYP2A6 (0.42) CYP2A6LPLLIPGCYP11B1CYP11B2
SCHEMBL322802 0.89 CYP2A6 (0.43) CYP2A6LPLLIPGCYP11B1CYP11B2
SCHEMBL431640 0.89 CYP2A6 (0.43) CYP2A6LPLLIPGCYP11B1CYP11B2
SCHEMBL2472423 0.88 CYP2A6 (0.42) CYP2A6LPLLIPGCYP11B1CYP11B2
SCHEMBL15731073 0.87 PGR (0.34) CYP2A6LPLLIPGCYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8841004-B2 Binaphthyl compound and organic light emitting element using the same CANON KABUSHIKI KAISHA (JP) 2014-09-23 US disclosed
US-20120061657-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-03-15 US disclosed