SCHEMBL3674564

SCHEMBL3674564

CC(C)CCCCCc1ccc(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
LMNA P02545 2/20 0.51
ALOX15 P16050 5/20 0.39
IGF1R P08069 4/20 0.39
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 2/20 0.37
HPGD P15428 2/20 0.37
POLB P06746 2/20 0.37
MAPK1 P28482 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TRPV1 Q8NER1 1/20 0.36
GRIN2D O15399 1/20 0.35
GRIN2A Q12879 1/20 0.35
GRIN2B Q13224 1/20 0.35
GRIN2C Q14957 1/20 0.35
MAPT P10636 1/20 0.35
CDK1 P06493 1/20 0.35
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26049543 0.90 NPC1 (0.56) NPC1RAB9ALMNAALOX15KDM4E
SCHEMBL11420436 0.88 NPC1 (0.50) NPC1RAB9ALMNAALOX15IGF1R
SCHEMBL11410372 0.88 KAT8 (0.41) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL3270039 0.88 NPC1 (0.48) NPC1RAB9ALMNAALOX15IGF1R
SCHEMBL16010672 0.86 IGF1R (0.41) NPC1RAB9ALMNAALOX15IGF1R
SCHEMBL3677611 0.86 LMNA (0.55) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL29360801 0.86 LMNA (0.55) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL30573271 0.86 LMNA (0.55) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL431307 0.86 LMNA (0.55) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL12755311 0.86 LMNA (0.55) NPC1RAB9ALMNAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106471043-B UV-active chromophore functionalized polysiloxanes and copolymers made therefrom 莫门蒂夫性能材料股份有限公司 2021-01-12 CN claimed
EP-3164446-B1 UV-ACTIVE CHROMOPHORE FUNCTIONALIZED POLYILOXANES AND COPOLYMERS MADE THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2019-11-20 EP claimed
EP-3164446-A1 UV-ACTIVE CHROMOPHORE FUNCTIONALIZED POLYILOXANES AND COPOLYMERS MADE THEREFROM Momentive Performance Materials Inc. (US) 2017-05-10 EP claimed
CN-106471043-A The polysiloxanes of chromophore functionalization of UV activity and the copolymer being made from 莫门蒂夫性能材料股份有限公司 2017-03-01 CN claimed
US-9562159-B2 UV-active chromophore functionalized polysiloxanes and copolymers made therefrom MOMENTIVE PERFORMANCE MATERIAL INC. (US) 2017-02-07 US claimed
WO-2016004287-A1 UV-ACTIVE CHROMOPHORE FUNCTIONALIZED POLYILOXANES AND COPOLYMERS MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-01-07 WO claimed
US-20160002412-A1 UV-ACTIVE CHROMOPHORE FUNCTIONALIZED POLYSILOXANES AND COPOLYMERS MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2016-01-07 US claimed
US-4600632-A COPOLYMER WITH POLYSILOXANE, BLOCK POLYMERS BAYER AKTIENGESELLSCHAFT (DE) 1986-07-15 US claimed
EP-3164446-B1 UV-ACTIVE CHROMOPHORE FUNCTIONALIZED POLYILOXANES AND COPOLYMERS MADE THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2019-11-20 EP disclosed
EP-3164446-A1 UV-ACTIVE CHROMOPHORE FUNCTIONALIZED POLYILOXANES AND COPOLYMERS MADE THEREFROM Momentive Performance Materials Inc. (US) 2017-05-10 EP disclosed
CN-106471043-A The polysiloxanes of chromophore functionalization of UV activity and the copolymer being made from 莫门蒂夫性能材料股份有限公司 2017-03-01 CN disclosed
US-9562159-B2 UV-active chromophore functionalized polysiloxanes and copolymers made therefrom MOMENTIVE PERFORMANCE MATERIAL INC. (US) 2017-02-07 US disclosed
WO-2016043983-A1 COMPOSITION WITH HIGH FILM FLEX ENDURANCE AND ARTICLES DERIVED THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-03-24 WO disclosed
US-20160002412-A1 UV-ACTIVE CHROMOPHORE FUNCTIONALIZED POLYSILOXANES AND COPOLYMERS MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2016-01-07 US disclosed
US-20040004652-A1 Ink jet recording method KONICA CORPORATION (JP) 2004-01-08 US disclosed
US-6055096-A Protective film of polarizing plate and polarizing plate KONICA CORPORATION (JP) 2000-04-25 US disclosed
US-4600632-A COPOLYMER WITH POLYSILOXANE, BLOCK POLYMERS BAYER AKTIENGESELLSCHAFT (DE) 1986-07-15 US disclosed
EP-0162245-A1 UV-stabilized polycarbonate moulding compositions BAYER AG (DE) 1985-11-27 EP disclosed
US-4220711-A Silver halide color photographic light-sensitive element FUJI PHOTO FILM CO., LTD. (JP) 1980-09-02 US disclosed
US-4009038-A CYAN COUPLER, A 2-(2'-HYDROXYPHENYL)BENZOTRIAZOLE FUJI PHOTO FILM CO., LTD. (JA) 1977-02-22 US disclosed