SCHEMBL3674577

SCHEMBL3674577

NCc1c(F)cc2ccccc2c1CN

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.67
ALDH1A1 P00352 3/20 0.48
TAAR1 Q96RJ0 2/20 0.48
KDM4E B2RXH2 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.45
LOXL2 Q9Y4K0 3/20 0.42
HPRT1 P00492 1/20 0.38
HSD17B10 Q99714 3/20 0.37
HIF1A Q16665 1/20 0.37
CYP1B1 Q16678 1/20 0.37
GPR35 Q9HC97 2/20 0.37
HTR1B P28222 2/20 0.35
CA12 O43570 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29439367 0.86 HTR2A (0.64) HTR2AALDH1A1TAAR1KDM4EGAA
SCHEMBL2384515 0.81 HTR2A (1.00) HTR2AALDH1A1TAAR1KDM4EGAA
SCHEMBL29758941 0.81 HTR2A (1.00) HTR2AALDH1A1TAAR1KDM4EGAA
SCHEMBL6399339 0.78 ALDH1A1 (0.60) HTR2AALDH1A1TAAR1KDM4EGAA
SCHEMBL3674867 0.76 HTR2A (0.67) HTR2AALDH1A1TAAR1KDM4EGAA
SCHEMBL3670705 0.76 HTR2A (0.67) HTR2AALDH1A1TAAR1KDM4EGAA
Hydrochloric Acid SCHEMBL20562119 0.76 HTR2A (0.46) HTR2AALDH1A1TAAR1MAPTL3MBTL1
SCHEMBL2381136 0.73 HTR2A (0.63) HTR2AALDH1A1TAAR1KDM4EGAA
SCHEMBL3674579 0.73 HTR2A (0.57) HTR2AALDH1A1TAAR1KDM4EGAA
SCHEMBL1264432 0.72 HTR2A (0.68) HTR2AALDH1A1TAAR1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1426392-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-02-24 EP disclosed
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed