SCHEMBL3674579

SCHEMBL3674579

NCc1cc2ccccc2c(F)c1CN

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.57
TAAR1 Q96RJ0 2/20 0.42
ALDH1A1 P00352 2/20 0.42
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
LOXL2 Q9Y4K0 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.38
PNMT P11086 1/20 0.36
CYP2A6 P11509 1/20 0.35
HIF1A Q16665 1/20 0.34
CYP1B1 Q16678 1/20 0.34
HSD17B10 Q99714 1/20 0.34
DPP4 P27487 2/20 0.34
CA2 P00918 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3670707 0.78 HTR2A (0.57) HTR2ATAAR1ALDH1A1KDM4EGAA
SCHEMBL3674869 0.78 HTR2A (0.57) HTR2ATAAR1ALDH1A1KDM4EGAA
SCHEMBL29439367 0.76 HTR2A (0.64) HTR2ATAAR1ALDH1A1KDM4EGAA
SCHEMBL6399345 0.75 ALDH1A1 (0.46) HTR2ATAAR1ALDH1A1KDM4EGAA
SCHEMBL15379970 0.75 HTR2A (0.52) HTR2ATAAR1ALDH1A1KDM4EGAA
SCHEMBL25416888 0.74 HTR2A (0.68) HTR2ATAAR1ALDH1A1KDM4EGAA
SCHEMBL8517693 0.74 HTR2A (0.56) HTR2ATAAR1ALDH1A1KDM4EGAA
SCHEMBL2384515 0.73 HTR2A (1.00) HTR2ATAAR1ALDH1A1KDM4EGAA
SCHEMBL29758941 0.73 HTR2A (1.00) HTR2ATAAR1ALDH1A1KDM4EGAA
SCHEMBL3674577 0.73 HTR2A (0.67) HTR2ATAAR1ALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1426392-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-02-24 EP disclosed
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed