SCHEMBL367478

SCHEMBL367478

C[C@H](N)C(=O)Oc1csc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.46
PKM P14618 1/20 0.42
MAPT P10636 4/20 0.40
MEN1 O00255 2/20 0.40
ALDH1A1 P00352 2/20 0.40
KMT2A Q03164 2/20 0.40
MAPK1 P28482 1/20 0.40
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HDAC9 Q9UKV0 1/20 0.40
HDAC5 Q9UQL6 1/20 0.40
APP P05067 1/20 0.38
CYP2A6 P11509 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23751272 1.00 ALOX5 (0.46) ALOX5PKMMAPTMEN1ALDH1A1
SCHEMBL23751269 1.00 ALOX5 (0.46) ALOX5PKMMAPTMEN1ALDH1A1
SCHEMBL31721993 1.00 ALOX5 (0.46) ALOX5PKMMAPTMEN1ALDH1A1
Hydrochloric Acid SCHEMBL28905944 0.98 ALOX5 (0.45) ALOX5PKMMAPTMEN1ALDH1A1
SCHEMBL16245939 0.82 SLC7A5 (0.42) PKMMAPTMEN1ALDH1A1KMT2A
SCHEMBL7032384 0.80 PKM (0.53) ALOX5PKMMAPTMEN1ALDH1A1
SCHEMBL27783140 0.79 PKM (0.46) PKMMAPTMEN1ALDH1A1KMT2A
SCHEMBL2025468 0.79 PKM (0.51) ALOX5PKMMAPTMEN1ALDH1A1
Biphenyl SCHEMBL28253359 0.79 CYP17A1 (0.37) ALOX5APPCNR2KDM4E
SCHEMBL5164703 0.77 HDAC3 (0.46) ALOX5PKMMAPTMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 634 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250339569-A1 CARBONIC ANHYDRASE IX LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2025-11-06 US claimed
US-20250250298-A1 ONCOLYTIC PEPTIDE AND USE THEREOF RISE BIOPHARMACEUTICALS INC. (CN) 2025-08-07 US claimed
WO-2025073102-A1 ONCOLYTIC PEPTIDE AND USE THEREOF FOR INHIBITING CANCER CELL VIABILITY LT BIOPHARMA INC. (CN) 2025-04-10 WO claimed
CN-119213011-A Radiolabeled compounds for in vivo imaging of the Gastrin Releasing Peptide Receptor (GRPR) and treatment of GRPR-related disorders 省卫生服务机构 2024-12-27 CN claimed
EP-4448544-A2 CARBONIC ANHYDRASE IX LIGANDS 3B Pharmaceuticals GmbH (DE) 2024-10-23 EP claimed
CN-118359680-A Semglutide derived stapling peptide and preparation method and application thereof 西安交通大学 2024-07-19 CN claimed
CN-117915957-A Compositions and methods for modulating mRNA splicing 恩特拉达治疗学股份有限公司 2024-04-19 CN claimed
CN-117561271-A Cyclic cell penetrating peptides 恩特拉达治疗公司 2024-02-13 CN claimed
EP-4294820-A1 CYCLIC CELL-PENETRATING PEPTIDES WITH THREE OR MORE HYDROPHOBIC RESIDUES Ohio State Innovation Foundation (US) 2023-12-27 EP claimed
WO-2023197129-A1 ONCOLYTIC PEPTIDE AND USE THEREOF RISE BIOPHARMACEUTICALS INC. (CN) 2023-10-19 WO claimed
US-20030166567-A1 Anti-aging and wound healing compounds KIMBERLY-CLARK WORLDWIDE, INC. 2003-09-04 US claimed
US-20030148959-A1 Anti-aging and wound healing compounds AVANOS MEDICAL SALES, LLC 2003-08-07 US claimed
WO-2003057820-A2 PEPTIDE ACTIVATORS OF VEGF KIMBERLY-CLARK WORLDWIDE, INC. (US) 2003-07-17 WO claimed
US-20030114362-A1 Penta-or tetrapeptide binding to somatostatin receptors and the use of the same NOVASPIN BIOTECH GMBH (DE) 2003-06-19 US claimed
US-20030096757-A1 Anti-cancer and wound healing compounds KIMBERLY-CLARK WORLDWIDE, INC. 2003-05-22 US claimed
WO-2003033528-A1 CYCLIC PEPTIDES AS G-PROTEIN-COUPLED RECEPTOR ANTAGONISTS UNIVERSITY OF QUEENSLAND (AU) 2003-04-24 WO claimed
WO-2003018748-A2 ANTI-CANCER AND WOUND HEALING COMPOUNDS KIMBERLY-CLARK WORLDWIDE, INC. (US) 2003-03-06 WO claimed
WO-2003016520-A1 ANTI-AGING AND WOUND HEALING COMPOUNDS KIMBERLY-CLARK WORLDWIDE, INC. (US) 2003-02-27 WO claimed
WO-2002100885-A2 A PENTA- OR TETRAPEPTIDE BINDING TO SOMATOSTATIN RECEPTORS AND THE USE OF THE SAME NOVASPIN BIOTECH GMBH (DE) 2002-12-19 WO claimed
CN-1234735-A Method for treating skin pigmentation JOHNSON & JOHNSON CONSUMER (US) 1999-11-10 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250339569-A1 CARBONIC ANHYDRASE IX LIGANDS CA9, CA13, CA4 ALOX5 3721/4885PKM 2993/4885MAPT 2838/4885
US-20030114362-A1 Penta-or tetrapeptide binding to somatostatin receptors and the use of the same SSTR5, SSTR3, SCTR ALOX5 329/4885PKM 2886/4885MAPT 2988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.