Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30824762 | 0.93 | MAOA (0.40) | GSTP1MAOAMAOBNPC1AKR1B1 | |
| SCHEMBL9797191 | 0.93 | MAOA (0.40) | GSTP1MAOAMAOBNPC1AKR1B1 | |
| SCHEMBL28438497 | 0.83 | HSD17B3 (0.47) | MAOAMAOBIDH1BACE1 | |
| SCHEMBL41940 | 0.83 | BACE1 (0.46) | MAOAMAOBHPGDBACE1 | |
| Benzene SCHEMBL29048034 | 0.83 | BACE1 (0.46) | MAOAMAOBHPGDBACE1 | |
| SCHEMBL30824732 | 0.82 | SRD5A2 (0.44) | HPGDTSHRRAB9A | |
| SCHEMBL29396532 | 0.82 | HTT (0.41) | MAOAMAOBNPC1TSHRRAB9A | |
| SCHEMBL30932196 | 0.82 | MAOA (0.45) | GSTP1MAOAMAOBXDH | |
| Hydrogen Sulfide SCHEMBL28559443 | 0.82 | HSD17B3 (0.46) | MAOAMAOBIDH1BACE1 | |
| SCHEMBL15841339 | 0.81 | BACE1 (0.45) | MAOAMAOBHPGDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825188-B2 | Thermoplastic elastomer with acyloxyphenyl hard block segment | DESIGNER MOLECULES, INC. (US) | 2010-11-02 | — | — | US | claimed |
| WO-2008077141-A1 | RUBBER EPOXY CURATIVES AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. (US) | 2008-06-26 | — | — | WO | claimed |
| US-20080146738-A1 | RUBBER EPOXY CURATIVES AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. | 2008-06-19 | — | — | US | claimed |
| US-7825188-B2 | Thermoplastic elastomer with acyloxyphenyl hard block segment | DESIGNER MOLECULES, INC. (US) | 2010-11-02 | — | — | US | disclosed |
| WO-2008077141-A1 | RUBBER EPOXY CURATIVES AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. (US) | 2008-06-26 | — | — | WO | disclosed |
| US-20080146738-A1 | RUBBER EPOXY CURATIVES AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. | 2008-06-19 | — | — | US | disclosed |
| US-4812244-A | SULFONATED STYRENE-MALEIMIDE COPOLYMER, SODIUM ACRYLATE-METHACRYLATE COPOLYMER | PONY INDUSTRIES, INC. (US) | 1989-03-14 | — | — | US | disclosed |
| EP-0304174-A2 | Bismaleimide compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-02-22 | — | — | EP | disclosed |
| US-4797450-A | PHENYLMALEIMIDES WITH STYRENE FOLLOWED BY SULFONATION | ARCO CHEMICAL COMPANY (US) | 1989-01-10 | — | — | US | disclosed |
| EP-0274203-A2 | Oligomers with pendant maleimide groups | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-07-13 | — | — | EP | disclosed |
| EP-0143508-A2 | Additive for water-base drilling fluid and process | ATLANTIC RICHFIELD COMPANY (US) | 1985-06-05 | — | — | EP | disclosed |