SCHEMBL9797191

SCHEMBL9797191

O=C1C=C(c2ccc(Oc3ccc(C4=CC(=O)NC4=O)cc3)cc2)C(=O)N1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.40
MAOB P27338 6/20 0.40
BACE1 P56817 2/20 0.38
GSTP1 P09211 1/20 0.37
TGM2 P21980 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
MCL1 Q07820 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
NPC1 O15118 1/20 0.35
MMP14 P50281 2/20 0.35
AKR1B1 P15121 1/20 0.33
HPGD P15428 1/20 0.33
GPR84 Q9NQS5 1/20 0.33
SLC2A1 P11166 1/20 0.32
MMP2 P08253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30824762 1.00 MAOA (0.40) MAOAMAOBBACE1GSTP1TGM2
SCHEMBL3675012 0.93 GSTP1 (0.49) MAOAMAOBBACE1GSTP1NPC1
SCHEMBL29396532 0.88 HTT (0.41) MAOAMAOBTGM2MAPTPKM
SCHEMBL30932196 0.88 MAOA (0.45) MAOAMAOBGSTP1TGM2
SCHEMBL30824732 0.88 SRD5A2 (0.44) MEN1MAPTMAPK1KMT2AHPGD
SCHEMBL448198 0.87 BACE1 (0.32) BACE1
SCHEMBL29458872 0.87 MMP14 (0.37) MAOAMAOBBACE1KDM4EMEN1
SCHEMBL16668754 0.85 HSD17B3 (0.34) MAOAMAOBBACE1
SCHEMBL3676452 0.85 BACE1 (0.58) BACE1KDM4EMEN1MAPTPKM
SCHEMBL31534288 0.83 LMNA (0.41) MAPTPKMGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116615468-A Polymer particles 昆士兰科技大学 2023-08-18 CN claimed
CN-120051648-A Rubber composition for rubber layer of laminated hose, and laminated hose for motor vehicle 住友理工株式会社 2025-05-27 CN disclosed
CN-119948083-A Curable composition 株式会社大赛璐 2025-05-06 CN disclosed
CN-116615468-A Polymer particles 昆士兰科技大学 2023-08-18 CN disclosed
CN-114096598-A Thermally expandable composition comprising a chemical blowing agent SIKA技术股份公司 2022-02-25 CN disclosed
EP-0409069-A2 Mesogenic polycyanates and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1991-01-23 EP disclosed
EP-0358084-A2 An adhesive system for bonding uncured rubber to cured polyurethane BRIDGESTONE/FIRESTONE, INC. (US) 1990-03-14 EP disclosed
EP-0031904-B1 HEAT-RESISTANT THERMOSETTING RESIN COMPOSITION KABUSHIKI KAISHA TOSHIBA (JP) 1984-05-16 EP disclosed