SCHEMBL3675129

SCHEMBL3675129

CC(Cl)C(=O)OCC(COC(=O)C(C)Cl)OC(=O)C(C)Cl

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
PRKCA P17252 2/20 0.35
TSHR P16473 2/20 0.33
SERPINE1 P05121 1/20 0.32
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3680973 0.82 TDP1 (0.36) TSHR
SCHEMBL27452776 0.78 TSHR (0.48) ALDH1A1LMNATSHR
SCHEMBL7675814 0.78 TSHR (0.48) ALDH1A1LMNATSHR
SCHEMBL5557909 0.77 TDP1 (0.46) TSHR
SCHEMBL3673935 0.77 TDP1 (0.41) TSHR
SCHEMBL3675892 0.77 TDP1 (0.46) TSHR
SCHEMBL2438756 0.76 LMNA (0.34) ALDH1A1LMNAPRKCASERPINE1PTPN1
SCHEMBL2402152 0.76 ALDH1A1 (0.38) ALDH1A1LMNAPRKCASERPINE1
SCHEMBL30531670 0.74 ALDH1A1 (0.37) ALDH1A1LMNAPRKCASERPINE1
SCHEMBL30531665 0.74 ALDH1A1 (0.37) ALDH1A1LMNAPRKCASERPINE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2013240-B1 PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS PIOTREK CO LTD (JP) 2017-05-31 EP disclosed
US-8492511-B2 Process for the preparation of crosslinked nitroxide polymers PIOTREK CO., LTD. (JP) 2013-07-23 US disclosed
US-20100240858-A1 PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS PIOTREK CO., LTD. (JP) 2010-09-23 US disclosed
EP-2013240-A1 PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS PIOTREK CO., LTD. (JP) 2009-01-14 EP disclosed
WO-2007115939-A1 PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS PIOTREK CO., LTD. (JP) 2007-10-18 WO disclosed