SCHEMBL3675285

SCHEMBL3675285

C=CCC(C)(C)OC(=O)C(=C)C

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
TSHR P16473 3/20 0.35
THRB P10828 1/20 0.33
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396135 0.82 ALDH1A1 (0.33) ALDH1A1TSHRTHRB
SCHEMBL16553409 0.82 ALDH1A1 (0.39) ALDH1A1TSHRTHRB
SCHEMBL5804465 0.81 GAA (0.41) ALDH1A1TSHRMAPT
SCHEMBL2641113 0.81 ALDH1A1 (0.35) ALDH1A1TSHRTHRB
SCHEMBL2143318 0.81 ALDH1A1 (0.35) ALDH1A1TSHRTHRB
SCHEMBL2688116 0.81 ALDH1A1 (0.35) ALDH1A1TSHRTHRB
SCHEMBL5523682 0.79 ALDH1A1 (0.34) ALDH1A1TSHRTHRB
SCHEMBL11224859 0.79 TSHR (0.33) ALDH1A1TSHR
SCHEMBL22353268 0.79 ALDH1A1 (0.44) ALDH1A1TSHRTHRB
SCHEMBL1067047 0.79 ALDH1A1 (0.44) ALDH1A1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1149867-B1 Crosslinked rubber particles and rubber compositions JSR CORP (JP) 2010-06-16 EP disclosed
US-6977286-B2 Crosslinked rubber particles and rubber compositions JSR CORPORATION (JP) 2005-12-20 US disclosed
US-20040152844-A1 Crosslinked rubber particles and rubber compositions JSR CORPORATION (JP) 2004-08-05 US disclosed
US-6747095-B2 CONJUGATED DIENE UNIT, AROMATIC VINYL UNIT, MONOMER UNIT HAVING TWO POLYMERIZABLE UNSATURATED GROUPS, MONOMER UNIT HAVING ONE POLYMERIZABLE UNSATURATED GROUP; DIMENSIONAL STABILITY JSR CORPORATION (JP) 2004-06-08 US disclosed
US-6559219-B2 Processability, and handling performance and dimension stability; to produce vulcanized rubber exhibiting wearing resistance and tensile strength useful in belts, hoses, and tires JSR CORPORATION (JP) 2003-05-06 US disclosed
US-20030008954-A1 Processability, and handling performance and dimension stability; to produce vulcanized rubber exhibiting wearing resistance and tensile strength useful in belts, hoses, and tires JSR CORPORATION (JP) 2003-01-09 US disclosed
US-20020007011-A1 Crosslinked rubber particles and rubber compositions JSR CORPORATION (JP) 2002-01-17 US disclosed
EP-1149866-A2 Rubber mixtures based on crosslinked rubber particles and non-crosslinked rubbers JSR Corporation (JP) 2001-10-31 EP disclosed
EP-1149867-A2 Crosslinked rubber particles and rubber compositions JSR Corporation (JP) 2001-10-31 EP disclosed