SCHEMBL396135

SCHEMBL396135

C=CC(C)=CCC(C)(C)OC(=O)C(=C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3675285 0.82 ALDH1A1 (0.38) ALDH1A1TSHRTHRB
SCHEMBL28747700 0.79 ALDH1A1 (0.33) ALDH1A1TSHRTHRB
SCHEMBL21716704 0.76 ALDH1A1 (0.34) ALDH1A1
SCHEMBL2688116 0.75 ALDH1A1 (0.35) ALDH1A1TSHRTHRB
SCHEMBL22353268 0.73 ALDH1A1 (0.44) ALDH1A1TSHRTHRB
SCHEMBL1067047 0.73 ALDH1A1 (0.44) ALDH1A1TSHRTHRB
SCHEMBL24282400 0.72 ALDH1A1 (0.46) ALDH1A1TSHRTHRB
Acrylamide SCHEMBL11512778 0.72 ALDH1A1 (0.38) ALDH1A1TSHRTHRB
SCHEMBL21496027 0.71 ALDH1A1 (0.42) ALDH1A1TSHRTHRB
SCHEMBL1371760 0.71 ALDH1A1 (0.42) ALDH1A1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1551885-B1 PROCESS TO MODIFY POLYMERIC MATERIALS 3M INNOVATIVE PROPERTIES CO (US) 2016-02-17 EP disclosed
US-8101711-B2 Process to modify polymeric materials and resulting compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-01-24 US disclosed
US-20100048819-A1 PROCESS TO MODIFY POLYMERIC MATERIALS AND RESULTING COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2010-02-25 US disclosed
US-7632916-B2 Thermally induced graft polymerization in an apparatus by shearing, devolatilization; grafting isoprene-t-butyl methacrylate copolymer with polyoxyethylene glycol methyl ether, forming methacrylic acid/anhydride monomers 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-15 US disclosed
US-20070122915-A1 Continuous process for the production of combinatorial libraries of modified materials 3M INNOVATIVE PROPETIES COMPANY 2007-05-31 US disclosed
US-7157283-B2 Continuous process for the production of combinatorial libraries of modified materials 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-01-02 US disclosed
EP-1551885-A2 PROCESS TO MODIFY POLYMERIC MATERIALS AND RESULTING COMPOSITIONS 3M Innovative Properties Company (US) 2005-07-13 EP disclosed
EP-1551547-A1 A CONTINUOUS PROCESS FOR THE PRODUCTION OF COMBINATORIAL LIBRARIES OF MODIFIED MATERIALS 3M Innovative Properties Company (US) 2005-07-13 EP disclosed
WO-2004012858-A1 A CONTINUOUS PROCESS FOR THE PRODUCTION OF COMBINATORIAL LIBRARIES OF MODIFIED MATERIALS 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-02-12 WO disclosed
WO-2004013189-A2 PROCESS TO MODIFY POLYMERIC MATERIALS AND RESULTING COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-02-12 WO disclosed
US-20040023398-A1 Continuous process for the production of combinatorial libraries of modified materials 3M INNOVATIVE PROPERTIES COMPANY 2004-02-05 US disclosed
US-20040024130-A1 Process to modify polymeric materials and resulting compositions 3M INNOVATIVE PROPERTIES COMPANY 2004-02-05 US disclosed