SCHEMBL3675366

SCHEMBL3675366

O=C(O)[C@@]1(CO)CCCN1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 3/20 0.54
ARG2 P78540 2/20 0.54
SLC6A2 P23975 10/20 0.35
SLC6A4 P31645 10/20 0.35
SLC6A3 Q01959 10/20 0.35
CYP2D6 P10635 9/20 0.35
KCNH2 Q12809 2/20 0.35
HRH3 Q9Y5N1 1/20 0.32
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3676543 1.00 ARG1 (0.54) ARG1ARG2SLC6A2SLC6A4SLC6A3
SCHEMBL28207275 1.00 ARG1 (0.54) ARG1ARG2SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL28206792 0.98 ARG1 (0.53) ARG1ARG2SLC6A2SLC6A4SLC6A3
SCHEMBL31603619 0.89
SCHEMBL28174553 0.85 ARG1 (0.53) ARG1ARG2SLC6A2SLC6A4SLC6A3
SCHEMBL30593437 0.81 ARG1 (0.53) ARG1ARG2SLC6A2SLC6A4SLC6A3
SCHEMBL5442859 0.81 ARG1 (0.53) ARG1ARG2SLC6A2SLC6A4SLC6A3
SCHEMBL30085352 0.81 ARG1 (0.53) ARG1ARG2SLC6A2SLC6A4SLC6A3
SCHEMBL1359695 0.81 ARG1 (0.53) ARG1ARG2SLC6A2SLC6A4SLC6A3
SCHEMBL1025995 0.81 ARG1 (0.41) ARG1ARG2SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250295157-A1 METHODS FOR THE IMPROVEMENT AND MAINTENANCE OF WEIGHT LOSS SOCIETE DES PRODUITS NESTLE S.A. (CH) 2025-09-25 US disclosed
US-12349713-B2 Methods for the improvement and maintenance of weight loss SOCIETE DES PRODUITS NESTLE S.A. (CH) 2025-07-08 US disclosed
EP-4099849-A1 COMPOSITIONS AND METHODS FOR THE IMPROVEMENT AND MAINTENANCE OF GLUCOSE METABOLISM IN CHILDHOOD AND ADOLESCENCE Société des Produits Nestlé S.A. (CH) 2022-12-14 EP disclosed
US-20220369685-A1 COMPOSITIONS AND METHODS FOR THE IMPROVEMENT AND MAINTENANCE OF GLUCOSE METABOLISM IN CHILDHOOD AND ADOLESCENCE NESTLE SA (CH) 2022-11-24 US disclosed
US-20220338521-A1 COMPOSITIONS AND METHODS FOR THE IMPROVEMENT AND MAINTENANCE OF WEIGHT LOSS SOCIETE DES PRODUITS NESTLE S.A. (CH) 2022-10-27 US disclosed
CN-114980753-A Compositions and methods for improving and maintaining glucose metabolism in children and adolescents 雀巢产品有限公司 2022-08-30 CN disclosed
CN-114423304-A Compositions and methods for improvement and maintenance of weight loss 雀巢产品有限公司 2022-04-29 CN disclosed
WO-2021156181-A1 COMPOSITIONS AND METHODS FOR THE IMPROVEMENT AND MAINTENANCE OF GLUCOSE METABOLISM IN CHILDHOOD AND ADOLESCENCE Société des Produits Nestlé S.A. (CH) 2021-08-12 WO disclosed
EP-3197445-B1 PROLINE OR PROLINE DERIVATIVES FOR THE TREATMENT OF DEMENTIA SALAMA ZOSER B (DE) 2021-04-28 EP disclosed
WO-2021058358-A1 COMPOSITIONS AND METHODS FOR THE IMPROVEMENT AND MAINTENANCE OF WEIGHT LOSS Société des Produits Nestlé S.A. (CH) 2021-04-01 WO disclosed
CN-105621408-A Method for manufacturing biomass powdered activated carbon by aid of loquat stone LIUZHOU DONGHOU BIOENERGY TECH CO LTD 2016-06-01 CN disclosed
WO-2016046162-A1 PROLINE OR PROLINE DERIVATIVES FOR THE TREATMENT OF DEMENTIA SALAMA ZOSER B (DE) 2016-03-31 WO disclosed
CN-105168762-A Medicament for treating stomach distension and preparation method thereof HUO CHUANSHENG 2015-12-23 CN disclosed
CN-104771513-A Traditional Chinese medicine composition for treating cholecystitis WANG YULING 2015-07-15 CN disclosed
CN-104758622-A Liver soothing and qi regulating preparation for patient with cholecystitis and preparation method of liver soothing and qi regulating preparation WANG YULING 2015-07-08 CN disclosed
US-7727530-B2 Anti-cancer composition comprising proline or its derivatives and an anti-tumour antibody SALAMA ZOSER B 2010-06-01 US disclosed
CN-1997365-A Anticancer composition containing proline or its derivative and antitumor antibody SALAMA ZOSER B (DE) 2007-07-11 CN disclosed
EP-1765328-A1 ANTI-CANCER COMPOSITION COMPRISING PROLINE OR ITS DERIVATIVES AND AN ANTI-TUMOUR ANTIBODY Salama, Zoser B. (DE) 2007-03-28 EP disclosed
WO-2005120495-A1 ANTI-CANCER COMPOSITION COMPRISING PROLINE OR ITS DERIVATIVES AND AN ANTI-TUMOUR ANTIBODY SALAMA ZOSER B (DE) 2005-12-22 WO disclosed
US-20050276810-A1 Anti-cancer composition comprising proline or its derivatives and an anti-tumour antibody SALAMA ZOSER B 2005-12-15 US disclosed