SCHEMBL3676543

SCHEMBL3676543

O=C(O)[C@]1(CO)CCCN1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 3/20 0.54
ARG2 P78540 2/20 0.54
SLC6A2 P23975 10/20 0.35
SLC6A4 P31645 10/20 0.35
SLC6A3 Q01959 10/20 0.35
CYP2D6 P10635 9/20 0.35
KCNH2 Q12809 2/20 0.35
HRH3 Q9Y5N1 1/20 0.32
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3675366 1.00 ARG1 (0.54) ARG1ARG2SLC6A2SLC6A4SLC6A3
SCHEMBL28207275 1.00 ARG1 (0.54) ARG1ARG2SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL28206792 0.98 ARG1 (0.53) ARG1ARG2SLC6A2SLC6A4SLC6A3
SCHEMBL31603619 0.89
SCHEMBL28174553 0.85 ARG1 (0.53) ARG1ARG2SLC6A2SLC6A4SLC6A3
SCHEMBL30593437 0.81 ARG1 (0.53) ARG1ARG2SLC6A2SLC6A4SLC6A3
SCHEMBL5442859 0.81 ARG1 (0.53) ARG1ARG2SLC6A2SLC6A4SLC6A3
SCHEMBL30085352 0.81 ARG1 (0.53) ARG1ARG2SLC6A2SLC6A4SLC6A3
SCHEMBL1359695 0.81 ARG1 (0.53) ARG1ARG2SLC6A2SLC6A4SLC6A3
SCHEMBL1025995 0.81 ARG1 (0.41) ARG1ARG2SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117815381-A Carbohydrate modified particles and particle formulations for modulating immune responses 西北大学 2024-04-05 CN claimed
CN-108024969-A Carbohydrate-modified particles and particle formulations for modulating immune responses 西北大学 2018-05-11 CN claimed
CN-106040301-A Polymer metal complex catalyst for synthesizing methyl isobutyl ketone 南京大学 2016-10-26 CN claimed
CN-105728040-A Preparation method of polymer catalyst for acetone condensation 南京大学 2016-07-06 CN claimed
CN-117815381-A Carbohydrate modified particles and particle formulations for modulating immune responses 西北大学 2024-04-05 CN disclosed
EP-4099849-A1 COMPOSITIONS AND METHODS FOR THE IMPROVEMENT AND MAINTENANCE OF GLUCOSE METABOLISM IN CHILDHOOD AND ADOLESCENCE Société des Produits Nestlé S.A. (CH) 2022-12-14 EP disclosed
EP-4033922-A1 COMPOSITIONS AND METHODS FOR THE IMPROVEMENT AND MAINTENANCE OF WEIGHT LOSS Société des Produits Nestlé S.A. (CH) 2022-08-03 EP disclosed
CN-114423304-A Compositions and methods for improvement and maintenance of weight loss 雀巢产品有限公司 2022-04-29 CN disclosed
WO-2021156181-A1 COMPOSITIONS AND METHODS FOR THE IMPROVEMENT AND MAINTENANCE OF GLUCOSE METABOLISM IN CHILDHOOD AND ADOLESCENCE Société des Produits Nestlé S.A. (CH) 2021-08-12 WO disclosed
WO-2021058358-A1 COMPOSITIONS AND METHODS FOR THE IMPROVEMENT AND MAINTENANCE OF WEIGHT LOSS Société des Produits Nestlé S.A. (CH) 2021-04-01 WO disclosed
CN-106040301-B A kind of high-molecule metal complex catalyst for synthesizing methyl isobutyl ketone 南京大学 2019-01-15 CN disclosed
CN-108024969-A Carbohydrate-modified particles and particle formulations for modulating immune responses 西北大学 2018-05-11 CN disclosed
CN-106040301-A Polymer metal complex catalyst for synthesizing methyl isobutyl ketone 南京大学 2016-10-26 CN disclosed
CN-105728040-A Preparation method of polymer catalyst for acetone condensation 南京大学 2016-07-06 CN disclosed
WO-2016046162-A1 PROLINE OR PROLINE DERIVATIVES FOR THE TREATMENT OF DEMENTIA SALAMA ZOSER B (DE) 2016-03-31 WO disclosed
US-7727530-B2 Anti-cancer composition comprising proline or its derivatives and an anti-tumour antibody SALAMA ZOSER B 2010-06-01 US disclosed
CN-1997365-A Anticancer composition containing proline or its derivative and antitumor antibody SALAMA ZOSER B (DE) 2007-07-11 CN disclosed
EP-1765328-A1 ANTI-CANCER COMPOSITION COMPRISING PROLINE OR ITS DERIVATIVES AND AN ANTI-TUMOUR ANTIBODY Salama, Zoser B. (DE) 2007-03-28 EP disclosed
WO-2005120495-A1 ANTI-CANCER COMPOSITION COMPRISING PROLINE OR ITS DERIVATIVES AND AN ANTI-TUMOUR ANTIBODY SALAMA ZOSER B (DE) 2005-12-22 WO disclosed
US-20050276810-A1 Anti-cancer composition comprising proline or its derivatives and an anti-tumour antibody SALAMA ZOSER B 2005-12-15 US disclosed