Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.93 |
| ▸ | TP53 | P04637 | 1/20 | 0.93 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.93 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.93 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.93 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.93 |
| ▸ | RECQL | P46063 | 1/20 | 0.93 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.93 |
| ▸ | CXCR4 | P61073 | 14/20 | 0.70 |
| ▸ | EBP | Q15125 | 1/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29373593 | 0.96 | MEN1 (1.00) | MEN1TP53CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7614558 | 0.96 | MEN1 (1.00) | MEN1TP53CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7614548 | 0.96 | MEN1 (1.00) | MEN1TP53CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL7920921 | 0.95 | MEN1 (0.96) | MEN1TP53CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL7920925 | 0.95 | MEN1 (0.96) | MEN1TP53CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL30545887 | 0.95 | MEN1 (0.96) | MEN1TP53CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5322402 | 0.88 | MEN1 (0.84) | MEN1TP53CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1966295 | 0.79 | MEN1 (0.70) | MEN1TP53CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6072254 | 0.77 | CHRM2 (0.72) | MEN1TP53CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25378299 | 0.75 | MEN1 (0.64) | MEN1TP53CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250333792-A1 | GENE PANEL FOR IDENTIFYING HYPO SEPSIS PHENOTYPE PATIENTS | UNIV FLORIDA (US) | 2025-10-30 | — | — | US | disclosed |
| WO-2024102834-A2 | COMPOUNDS AND METHODS FOR TREATING SEPSIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-05-16 | — | — | WO | disclosed |
| CN-116059364-A | Application of DHCR7 down-regulator in weakening alcohol-induced liver tumor | 上海健康医学院 | 2023-05-05 | — | — | CN | disclosed |
| CN-112691094-B | Novel compound for preventing and treating virus and application thereof | 中国科学院分子细胞科学卓越创新中心 | 2022-09-23 | — | — | CN | disclosed |
| CN-112691094-A | Novel compound for preventing and treating virus and application thereof | 中国科学院分子细胞科学卓越创新中心 | 2021-04-23 | — | — | CN | disclosed |
| US-20100092479-A1 | Compositions and methods for treatment of viral diseases | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-04-15 | — | — | US | disclosed |
| WO-2010021681-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100092479-A1 | Compositions and methods for treatment of viral diseases | HAVCR2, RNASE1, EIF2AK2 | CHRM2 4860/4885MEN1 4176/4885TP53 796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.