Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 15/20 | 0.85 |
| ▸ | CCNE1 | P24864 | 13/20 | 0.85 |
| ▸ | CDK9 | P50750 | 8/20 | 0.85 |
| ▸ | CDK5 | Q00535 | 7/20 | 0.85 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.85 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.85 |
| ▸ | CDK1 | P06493 | 8/20 | 0.70 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.70 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.70 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.70 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.70 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.70 |
| ▸ | CCNT2 | O60583 | 1/20 | 0.70 |
| ▸ | CDK7 | P50613 | 6/20 | 0.68 |
| ▸ | CCNH | P51946 | 4/20 | 0.68 |
| ▸ | CCNK | O75909 | 4/20 | 0.68 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.68 |
| ▸ | CDK4 | P11802 | 3/20 | 0.68 |
| ▸ | CCND1 | P24385 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15117748 | 0.92 | CDK2 (1.00) | CDK2CCNE1CDK9CDK5CCNT1 | |
| SCHEMBL1353962 | 0.91 | CDK2 (0.82) | CDK2CCNE1CDK9CDK5CCNT1 | |
| SCHEMBL3679696 | 0.88 | CDK1 (0.70) | CDK2CCNE1CDK9CDK5CCNT1 | |
| SCHEMBL15117914 | 0.85 | CDK2 (0.87) | CDK2CCNE1CDK9CDK5CCNT1 | |
| SCHEMBL1441193 | 0.84 | CDK2 (0.85) | CDK2CCNE1CDK9CDK5CCNT1 | |
| SCHEMBL15117892 | 0.83 | CDK2 (1.00) | CDK2CCNE1CDK9CDK5CCNT1 | |
| Olomoucine Ii SCHEMBL786673 | 0.83 | CDK2 (1.00) | CDK2CCNE1CDK9CDK5CCNT1 | |
| Olomoucine Ii SCHEMBL3514137 | 0.83 | CDK2 (1.00) | CDK2CCNE1CDK9CDK5CCNT1 | |
| Olomoucine Ii SCHEMBL31069520 | 0.83 | CDK2 (1.00) | CDK2CCNE1CDK9CDK5CCNT1 | |
| SCHEMBL15118130 | 0.82 | CDK2 (1.00) | CDK2CCNE1CDK9CDK5CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764118-B1 | Polymer coating for medical devices | GILEAD PALO ALTO INC (US) | 2010-08-25 | — | — | EP | disclosed |
| US-20080160166-A1 | POLYMER COATING FOR MEDICAL DEVICES | RYPACEK FRANTISEK | 2008-07-03 | — | — | US | disclosed |
| EP-1492581-B1 | POLYMER COATING FOR MEDICAL DEVICES | CV THERAPEUTICS INC (US) | 2006-12-20 | — | — | EP | disclosed |