Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12499996 | 0.98 | GRIN1 (0.33) | GRIN1GRIN2AGRIN2BSLC6A4GRIN2D | |
| SCHEMBL6282686 | 0.93 | MAPT (0.30) | TSHR | |
| SCHEMBL7776154 | 0.76 | — | — | |
| SCHEMBL10888167 | 0.76 | — | — | |
| SCHEMBL29013944 | 0.76 | GRIN1 (0.36) | GRIN1GRIN2AGRIN2BSLC6A4GRIN2D | |
| SCHEMBL7619912 | 0.76 | SLC6A4 (0.30) | GRIN1GRIN2AGRIN2BSLC6A4GRIN2D | |
| SCHEMBL23168690 | 0.74 | GRIN1 (0.33) | GRIN1GRIN2AGRIN2BSLC6A4GRIN2D | |
| SCHEMBL1627516 | 0.73 | — | — | |
| SCHEMBL11164661 | 0.70 | TSHR (0.40) | TSHR | |
| SCHEMBL4605079 | 0.70 | GRIN1 (0.38) | GRIN1GRIN2AGRIN2BGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7652172-B2 | Expeditious synthesis of DPD | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2010-01-26 | — | — | US | claimed |
| CN-101494999-A | Method for using organic compound | GIVAUDAN SA (CH) | 2009-07-29 | — | — | CN | claimed |
| US-20090018368-A1 | EXPEDITIOUS SYNTHESIS OF DPD | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2009-01-15 | — | — | US | claimed |
| WO-2006034269-A1 | EXPEDITIOUS SYNTHESIS OF DPD | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2006-03-30 | — | — | WO | claimed |
| WO-2025014332-A1 | TRIAZOLE COMPOUND HAVING NOVEL RING STRUCTURE, METHOD FOR PREPARING SAME, AND USE THEREOF | 한국화학연구원 | 2025-01-16 | — | — | WO | disclosed |
| US-8436005-B2 | Macrocyclic pyrimidine derivatives | ABBOTT LABORATORIES (US) | 2013-05-07 | — | — | US | disclosed |
| US-7652172-B2 | Expeditious synthesis of DPD | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2010-01-26 | — | — | US | disclosed |
| WO-2009123967-A1 | 5,6,7,8-TETRAHYDROQUINAZOLIN-2-AMINE DERIVATIVES AND RELATED COMPOUNDS AS HISTAMINE H4 RECEPTOR MODULATORS FOR THE TREATMENT OF ASTHMA | ABBOTT LABORATORIES (US) | 2009-10-08 | — | — | WO | disclosed |
| US-20090253678-A1 | MACROCYCLIC PYRIMIDINE DERIVATIVES | ABBOTT LABORATORIES (US) | 2009-10-08 | — | — | US | disclosed |
| CN-101494999-A | Method for using organic compound | GIVAUDAN SA (CH) | 2009-07-29 | — | — | CN | disclosed |
| US-20090018368-A1 | EXPEDITIOUS SYNTHESIS OF DPD | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2009-01-15 | — | — | US | disclosed |
| WO-2006034269-A1 | EXPEDITIOUS SYNTHESIS OF DPD | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2006-03-30 | — | — | WO | disclosed |
| US-5407931-A | Bactericides | GLAXO S.P.A. (IT) | 1995-04-18 | — | — | US | disclosed |
| EP-0385336-B1 | PROCESSES FOR THE PREPARATION OF PTERIN DERIVATIVES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-5138048-A | 4-(2-OXO-CYCLOHEXYL) AZETIDINONES | GLAXO S.P.A. (IT) | 1992-08-11 | — | — | US | disclosed |
| US-5043446-A | Subjecting ribose to acetalization, Grignard, oxidative cleavage, hydrazoning, condensing with pyridine to 1-biopterin | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-08-27 | — | — | US | disclosed |
| EP-0416952-A2 | 4-(1'-Oxocyclohex-2'-yl)azetidin-2-one derivatives | GLAXO S.p.A. (IT) | 1991-03-13 | — | — | EP | disclosed |
| EP-0416953-A2 | 10-(1-Hydroxyethyl)-11-oxo-1-azatricyclo[7.2.0.0.3,8]undec-2-ene-2-carboxylic acid derivatives | GLAXO S.p.A. (IT) | 1991-03-13 | — | — | EP | disclosed |
| EP-0385336-A2 | Processes for the preparation of pterin derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-09-05 | — | — | EP | disclosed |
| US-4393215-A | Cleavage of dialkoxyketoxime | ALLIED CORPORATION (US) | 1983-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253678-A1 | MACROCYCLIC PYRIMIDINE DERIVATIVES | DPYD, TYMS, TYMP | GRIN1 3329/4885GRIN2A 3384/4885GRIN2B 3499/4885 |
| US-20090018368-A1 | EXPEDITIOUS SYNTHESIS OF DPD | PGD, DBI, DPY30 | GRIN1 3638/4885GRIN2A 4087/4885GRIN2B 4025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.