Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654847 | 0.78 | GRIN2D (0.35) | GRIN1GRIN2AGRIN2BGRIN2DGRIN3B | |
| SCHEMBL15375840 | 0.75 | CPB2 (0.31) | — | |
| SCHEMBL16283884 | 0.72 | GRIN2D (0.31) | GRIN1GRIN2AGRIN2BGRIN2DGRIN3B | |
| SCHEMBL1254598 | 0.72 | MAPT (0.31) | TSHR | |
| SCHEMBL3676099 | 0.70 | GRIN1 (0.34) | GRIN1GRIN2AGRIN2BGRIN2DGRIN3B | |
| SCHEMBL2692225 | 0.70 | GRIN1 (0.42) | GRIN1GRIN2AGRIN2BGRIN2DGRIN3B | |
| SCHEMBL8315536 | 0.68 | CYP19A1 (0.33) | GRIN1GRIN2AGRIN2BGRIN2DGRIN3B | |
| SCHEMBL23168690 | 0.68 | GRIN1 (0.33) | GRIN1GRIN2AGRIN2BGRIN2DGRIN3B | |
| SCHEMBL15658952 | 0.68 | GRIN1 (0.41) | GRIN1GRIN2AGRIN2BGRIN2DGRIN3B | |
| SCHEMBL3531548 | 0.68 | GRIN1 (0.41) | GRIN1GRIN2AGRIN2BGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943218-B1 | ALKOXYALKYL SPIROCYCLIC TETRAMIC ACIDS AND TETRONIC ACIDS | BAYER IP GMBH (DE) | 2015-05-06 | — | — | EP | disclosed |
| EP-1943218-A2 | ALKOXYALKYL SPIROCYCLIC TETRAMIC ACIDS AND TETRONIC ACIDS | Bayer CropScience AG (DE) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007048545-A2 | ALKOXYALKYL SPIROCYCLIC TETRAMIC ACIDS AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2007-05-03 | — | — | WO | disclosed |