SCHEMBL230028

SCHEMBL230028

C=C(C)C(=O)OCCCCO[SiH](C)C

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.61
POLB P06746 1/20 0.50
APEX1 P27695 1/20 0.50
HTT P42858 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
THRB P10828 1/20 0.48
ALDH1A1 P00352 5/20 0.38
CYP3A4 P08684 1/20 0.32
NAAA Q02083 1/20 0.31
RAD52 P43351 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9067880 0.98 TSHR (0.65) TSHRPOLBAPEX1HTTTDP1
SCHEMBL26918976 0.98 TSHR (0.65) TSHRPOLBAPEX1HTTTDP1
SCHEMBL9173067 0.98 TSHR (0.65) TSHRPOLBAPEX1HTTTDP1
SCHEMBL8522863 0.96 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
SCHEMBL1536163 0.88 THRB (0.57) TSHRPOLBAPEX1HTTTDP1
SCHEMBL5144090 0.85 TSHR (0.79) TSHRPOLBAPEX1HTTTDP1
SCHEMBL25426 0.85 TSHR (0.79) TSHRPOLBAPEX1HTTTDP1
SCHEMBL15901753 0.85 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL9469051 0.84 TSHR (0.45) TSHRPOLBAPEX1HTTTDP1
SCHEMBL22554404 0.83 TSHR (0.83) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 312 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117209673-B Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2024-04-26 CN claimed
CN-117209673-A Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2023-12-12 CN claimed
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN claimed
CN-106866971-B Weather-resistant low-temperature-resistant organic silicon impact modifier and preparation method and application thereof 广东优科艾迪高分子材料有限公司 2020-05-05 CN claimed
US-6281297-B1 CONTAINING ALLYL METHACRYLATE AND ORGANOSILICON COMPOUND KANEKA CORPORATION (JP) 2001-08-28 US claimed
US-12030973-B2 Thermoplastic resin composition and molded article of same TECHNO-UMG CO., LTD. (JP) 2024-07-09 US disclosed
US-20240158904-A1 UNDERCOAT AGENT COMPOSITION FOR LAYERING INORGANIC MATERIAL LAYER, CURED PRODUCT THEREOF AND PRODUCTION METHOD THEREOF TOAGOSEI CO., LTD. (JP) 2024-05-16 US disclosed
EP-3543246-B1 COMPOSITION CONTAINING ORGANIC SILICON COMPOUND AND PAINT AND ADHESIVE CONTAINING SAID COMPOSITION SHINETSU CHEMICAL CO (JP) 2024-05-15 EP disclosed
US-11976189-B2 Thermoplastic resin composition and molded article TECHNO-UMG CO., LTD. (JP) 2024-05-07 US disclosed
CN-117209673-B Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2024-04-26 CN disclosed
US-20240092961-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE OF SAME TECHNO-UMG CO., LTD. (JP) 2024-03-21 US disclosed
US-20240043678-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE TECHNO-UMG CO., LTD. (JP) 2024-02-08 US disclosed
US-4994522-A Blends with polysiloxane rubbers which also have grafted acrylic ester monomers; impact strength, moldings MITSUBISHI RAYON COMPANY LIMITED (JP) 1991-02-19 US disclosed
US-4918132-A Thermoplastic polyester resin composition MITSUBISHI RAYON COMPANY LIMITED (JP) 1990-04-17 US disclosed
US-4894415-A BLENDS, FRAFT COPOLYMERS, POLYALKYL (METH)ACRYLATE MITSUBISHI RAYON CO., LTD. (JP) 1990-01-16 US disclosed
US-4892900-A CONTAINING POLYSILOXANE GRAFT POLYMER, IMPROVED IMPACT STRENGTH MITSUBISHI RAYON CO., LTD. (JP) 1990-01-09 US disclosed
US-4888388-A BLENDS WITH POLYESTERS AND GRAFTED POLYSILOXANE-ACRYLIC POLYMERS MITSUBISHI RAYON COMPANY LIMITED (JP) 1989-12-19 US disclosed
EP-0308871-A2 Thermoplastic polyester resin composition MITSUBISHI RAYON CO., LTD. (JP) 1989-03-29 EP disclosed
US-4775712-A BLENDS WITH POLYSILOXANES-IMPACT STRENGTH, HEAT AND COLD RESISTANT, WEATHERPROOFING-MOLDING MATERIALS MITSUBISHI RAYON CO., LTD. (JP) 1988-10-04 US disclosed
EP-0260552-A2 Graft copolymer rubber and polyphenylene ether resin composition comprising this rubber. MITSUBISHI RAYON CO., LTD. (JP) 1988-03-23 EP disclosed