Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229156 | 0.94 | ELANE (0.50) | ELANERAB9ALMNAATML3MBTL1 | |
| SCHEMBL9485663 | 0.89 | ELANE (0.53) | ELANERAB9ALMNAATML3MBTL1 | |
| SCHEMBL31627961 | 0.84 | GAA (0.57) | RAB9ALMNAKMT2AMEN1MAPT | |
| SCHEMBL6663601 | 0.81 | KMT2A (0.53) | L3MBTL1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL11845210 | 0.81 | PTGS1 (0.51) | LMNAMAPTALDH1A1HTTPOLB | |
| SCHEMBL21795326 | 0.80 | ELANE (0.79) | ELANERAB9ALMNAATML3MBTL1 | |
| SCHEMBL11218289 | 0.78 | NPC1 (0.57) | ELANERAB9ALMNAKMT2AMEN1 | |
| SCHEMBL8346992 | 0.77 | ELANE (0.47) | ELANERAB9ALMNAATML3MBTL1 | |
| SCHEMBL8346993 | 0.77 | ELANE (0.47) | ELANERAB9ALMNAATML3MBTL1 | |
| SCHEMBL23493150 | 0.76 | ELANE (0.55) | ELANERAB9ALMNAATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013240-B1 | PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS | PIOTREK CO LTD (JP) | 2017-05-31 | — | — | EP | disclosed |
| US-8492511-B2 | Process for the preparation of crosslinked nitroxide polymers | PIOTREK CO., LTD. (JP) | 2013-07-23 | — | — | US | disclosed |
| CN-101490100-B | Process for the preparation of crosslinked nitroxide polymers | PIOTREK CO LTD | 2012-08-22 | — | — | CN | disclosed |
| US-20100240858-A1 | PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS | PIOTREK CO., LTD. (JP) | 2010-09-23 | — | — | US | disclosed |
| CN-101490100-A | Process for the preparation of crosslinked nitroxide polymers | PIOTREK CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |
| EP-2013240-A1 | PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS | PIOTREK CO., LTD. (JP) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007115939-A1 | PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS | PIOTREK CO., LTD. (JP) | 2007-10-18 | — | — | WO | disclosed |