SCHEMBL3676524

SCHEMBL3676524

c1ccc([SiH2]O[SiH](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.31
TSHR P16473 1/20 0.31
NAPRT Q6XQN6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30407807 0.83
SCHEMBL28253477 0.79
SCHEMBL11113803 0.79
SCHEMBL3948344 0.79 MAPT (0.30) TSHR
SCHEMBL7528417 0.77 CA4 (0.32) TSHR
SCHEMBL18625997 0.76 CA4 (0.30)
SCHEMBL6972085 0.75 ALDH1A1 (0.31) TSHRNAPRT
SCHEMBL5008757 0.75 TSHR (0.31) DAOTSHRNAPRT
SCHEMBL10586964 0.75
SCHEMBL27689491 0.75 TSHR (0.31) DAOTSHRNAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7737291-B2 2,4,6,8-tetramethylcyclotetrasiloxane and stabilizer used as a material for thin film formation by chemical vapor deposition, or atomic layer deposition ADEKA CORPORATION (JP) 2010-06-15 US disclosed
US-20070232821-A1 Composition Containing Siloxane Compound and Phenol Compound ADEKA CORPORATION (JP) 2007-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070232821-A1 Composition Containing Siloxane Compound and Phenol Compound H1-0, CYP2S1, H1-4 DAO 1092/4885TSHR 3513/4885NAPRT 3834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.