Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.30 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693762 | 0.81 | HPGD (0.32) | ALDH1A1HPGD | |
| SCHEMBL49492 | 0.81 | ALDH1A1 (0.42) | ALDH1A1CES2CES1HPGDLMNA | |
| SCHEMBL3676524 | 0.75 | DAO (0.31) | TSHRNAPRT | |
| SCHEMBL29026463 | 0.72 | ELANE (0.43) | ALDH1A1CES2CES1LMNAL3MBTL1 | |
| SCHEMBL1053847 | 0.72 | ELANE (0.43) | ALDH1A1LMNAL3MBTL1TSHR | |
| SCHEMBL50084 | 0.70 | — | — | |
| SCHEMBL5008757 | 0.70 | TSHR (0.31) | ALDH1A1CA4ALOX15TSHRNAPRT | |
| SCHEMBL11113803 | 0.70 | — | — | |
| SCHEMBL28867306 | 0.70 | LMNA (0.54) | ALDH1A1CES2CES1LMNAMAPK1 | |
| SCHEMBL3679065 | 0.69 | TSHR (0.37) | ALDH1A1CA4HPGDLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |