SCHEMBL3676531

SCHEMBL3676531

CC(C)N(C)S(=O)(=O)NC(=O)c1ccccc1F

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.55
POLB P06746 2/20 0.54
GAA P10253 1/20 0.51
KAT6A Q92794 4/20 0.48
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
LMNA P02545 3/20 0.46
NPC1 O15118 2/20 0.46
MAPT P10636 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TP53 P04637 1/20 0.46
NFKB1 P19838 1/20 0.46
RAB9A P51151 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
ALDH1A1 P00352 1/20 0.45
KDM4E B2RXH2 1/20 0.45
SCN9A Q15858 2/20 0.45
HDAC3 O15379 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28176145 0.86 HPGD (0.59) HPGDPOLBGAAKAT6AMEN1
SCHEMBL27958411 0.84 HPGD (0.51) HPGDPOLBGAAKAT6AMEN1
SCHEMBL7987848 0.78 HPGD (0.61) HPGDPOLBGAAKAT6AMEN1
SCHEMBL27881580 0.78 HDAC1 (0.47) HPGDGAAMEN1KMT2ALMNA
SCHEMBL365236 0.77 HPGD (0.65) HPGDPOLBGAAKAT6AMEN1
Fluoride SCHEMBL31738472 0.76 HTT (0.46) HPGDGAAMEN1KMT2ALMNA
SCHEMBL27871304 0.75 ALDH1A1 (0.49) HPGDGAAKMT2ALMNANPC1
SCHEMBL7991909 0.74 HPGD (0.56) HPGDPOLBGAAKAT6AMEN1
SCHEMBL28018539 0.74 HPGD (0.65) HPGDPOLBGAAKAT6AMEN1
SCHEMBL26563083 0.73 CYP1A2 (0.43) SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2157856-A1 HERBICIDALLY EFFECTIVE COMPOSITION Basf Se (DE) 2010-03-03 EP disclosed
WO-2008152074-A1 HERBICIDALLY EFFECTIVE COMPOSITION BASF SE (DE) 2008-12-18 WO disclosed