Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3676531 | 0.86 | HPGD (0.55) | HPGDPOLBGAASCN9AMEN1 | |
| SCHEMBL10768712 | 0.81 | ALDH1A1 (0.49) | POLBGAASCN9AMEN1KMT2A | |
| SCHEMBL365236 | 0.81 | HPGD (0.65) | HPGDPOLBGAASCN9AMEN1 | |
| SCHEMBL15094270 | 0.81 | SCN9A (0.54) | SCN9A | |
| SCHEMBL27958411 | 0.79 | HPGD (0.51) | HPGDPOLBGAAMEN1KMT2A | |
| SCHEMBL7987848 | 0.78 | HPGD (0.61) | HPGDPOLBGAAMEN1KMT2A | |
| SCHEMBL15017840 | 0.78 | SCN9A (0.57) | SCN9A | |
| SCHEMBL28018539 | 0.77 | HPGD (0.65) | HPGDPOLBGAAMEN1KMT2A | |
| SCHEMBL15536401 | 0.75 | SCN9A (0.44) | SCN9AALDH1A1 | |
| SCHEMBL11266031 | 0.75 | HPGD (1.00) | HPGDPOLBGAAKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428683-A | N sulphonyl yl-benzamide derivatives, its preparation method and the purposes pharmaceutically of heterocyclic substituted | 上海海雁医药科技有限公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-107406380-A | N sulphonyl yl-benzamide derivatives, its preparation method and the purposes pharmaceutically of heterocyclic substituted | 上海海雁医药科技有限公司 | 2017-11-28 | — | — | CN | disclosed |
| CN-107108517-A | Sodium channel blockers | 株式会社大熊制药 | 2017-08-29 | — | — | CN | disclosed |