SCHEMBL3676532

SCHEMBL3676532

CC(C)N(C)S(=O)(=O)N(F)C(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.47
MLYCD O95822 1/20 0.43
LIMK2 P53671 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
NR3C2 P08235 2/20 0.37
NR1H2 P55055 1/20 0.37
NR1H3 Q13133 1/20 0.37
ADAMTS4 O75173 1/20 0.37
HPGD P15428 2/20 0.37
ALDH1A1 P00352 1/20 0.37
PGR P06401 1/20 0.37
ADRA2A P08913 1/20 0.37
ADRA2B P18089 1/20 0.37
HTR2A P28223 1/20 0.37
HRH1 P35367 1/20 0.37
KCNH2 Q12809 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
RAB9A P51151 2/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL365237 0.77 HSD11B1 (0.50) HSD11B1MLYCDNR3C2NR1H2NR1H3
SCHEMBL3377195 0.74 MLYCD (0.50) HSD11B1MLYCDNPSR1TRPM8HPGD
SCHEMBL394512 0.72 HSD11B1 (0.53) HSD11B1MLYCDLIMK2NPSR1TRPM8
SCHEMBL11832256 0.72 HSD11B1 (0.52) HSD11B1NR3C2HPGDALDH1A1L3MBTL1
SCHEMBL2351713 0.72 HSD11B1 (0.52) HSD11B1NR1H2NR1H3HPGDALDH1A1
Hydrochloric Acid SCHEMBL27873129 0.70 HSD11B1 (0.50) HSD11B1NR1H2NR1H3HPGDALDH1A1
SCHEMBL458409 0.70 NPSR1 (0.59) HSD11B1MLYCDNPSR1TRPM8HPGD
SCHEMBL13571402 0.70 MLYCD (0.53) HSD11B1MLYCDNPSR1TRPM8HPGD
SCHEMBL26015707 0.69 HSD11B1 (0.46) HSD11B1MLYCDLIMK2NPSR1TRPM8
Hydrochloric Acid SCHEMBL31125741 0.69 NPSR1 (0.57) HSD11B1MLYCDNPSR1TRPM8HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2157856-A1 HERBICIDALLY EFFECTIVE COMPOSITION Basf Se (DE) 2010-03-03 EP disclosed
WO-2008152074-A1 HERBICIDALLY EFFECTIVE COMPOSITION BASF SE (DE) 2008-12-18 WO disclosed