SCHEMBL3676568

SCHEMBL3676568

Cc1cccc(F)c1C(N)N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.48
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
SCN4A P35499 5/20 0.35
CYP1A2 P05177 3/20 0.35
MAOA P21397 2/20 0.35
LMNA P02545 2/20 0.35
SCN1A P35498 2/20 0.35
SCN5A Q14524 2/20 0.35
SCN9A Q15858 2/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2D6 P10635 2/20 0.35
TSHR P16473 2/20 0.35
NFKB1 P19838 2/20 0.35
HTR2A P28223 2/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20256245 0.83 CES2 (0.41) ACHECYP3A4HTR2ACES2CES1
SCHEMBL6732981 0.83 CA1 (0.48) ACHECA1CA2CA7CA9
SCHEMBL21884017 0.79 ACHE (0.41) ACHECA1CA2CA7CA9
SCHEMBL8246278 0.79 ACHE (0.50) ACHECA1CA2CA7CA9
SCHEMBL24130172 0.77 ACHE (0.48) ACHECA1CA2CA7CA9
SCHEMBL24117088 0.77 ACHE (0.48) ACHECA1CA2CA7CA9
SCHEMBL22728357 0.76 ACHE (0.46) ACHECA1CA2CA7CA9
SCHEMBL21612984 0.76 ACHE (0.46) ACHECA1CA2CA7CA9
SCHEMBL19682345 0.76 ACHE (0.46) ACHECA1CA2CA7CA9
SCHEMBL13266585 0.74 ACHE (0.44) ACHECA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1426392-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-02-24 EP disclosed
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed