Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 6/20 | 0.66 |
| ▸ | HTR3B | O95264 | 6/20 | 0.66 |
| ▸ | HTR3A | P46098 | 6/20 | 0.66 |
| ▸ | HTR3D | Q70Z44 | 6/20 | 0.66 |
| ▸ | HTR3C | Q8WXA8 | 6/20 | 0.66 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.66 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.66 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.66 |
| ▸ | PLAU | P00749 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10807881 | 0.82 | HTR3E (0.57) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL3779968 | 0.79 | HTR3E (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9750167 | 0.78 | NOS1 (0.57) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL28630854 | 0.78 | HTR3E (0.96) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL1490350 | 0.76 | PARP1 (0.52) | KMT2AMEN1PARP1MAPTALDH1A1 | |
| SCHEMBL1515207 | 0.76 | HTR3E (0.66) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL10740210 | 0.76 | HTR3E (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Urea SCHEMBL29193198 | 0.75 | PARP1 (0.67) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL4587367 | 0.74 | CYP2C19 (0.54) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL10794558 | 0.73 | HTR3E (0.64) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250319-A | RIPENER FOR SUGARCANE | W. R. GRACE & CO. (US) | 1981-02-10 | — | — | US | claimed |
| EP-2167090-A2 | HDAC INHIBITORS AND HORMONE TARGETED DRUGS FOR THE TREATMENT OF CANCER | University of Maryland, Baltimore (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008154402-A2 | HDAC INHIBITORS AND HORMONE TARGETED DRUGS FOR THE TREATMENT OF CANCER | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2008-12-18 | — | — | WO | disclosed |
| US-3989505-A | Use of polycyclic thiophene compounds as ripeners for sugarcane | HAWAIIAN SUGAR PLANTERS' ASSOCIATION (US) | 1976-11-02 | — | — | US | disclosed |