SCHEMBL3676779

SCHEMBL3676779

CCCCCCCCNc1cc(O)ncn1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM2 P50570 6/20 0.63
GPR84 Q9NQS5 4/20 0.46
S1PR2 O95136 1/20 0.43
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
HCAR3 P49019 1/20 0.43
FLT3 P36888 2/20 0.43
TYRO3 Q06418 2/20 0.43
MERTK Q12866 2/20 0.43
GAS6 Q14393 2/20 0.43
SOAT1 P35610 2/20 0.40
CDC7 O00311 1/20 0.40
ROCK2 O75116 1/20 0.40
MAP4K4 O95819 1/20 0.40
PIM1 P11309 1/20 0.40
PRKACA P17612 1/20 0.40
CDK2 P24941 1/20 0.40
GSK3B P49841 1/20 0.40
HIPK2 Q9H2X6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31696268 0.86 DNM2 (0.45) DNM2LMNASMN1; SMN2HCAR3FLT3
SCHEMBL5665700 0.78 DNM2 (0.60) DNM2S1PR2LMNASMN1; SMN2NPSR1
SCHEMBL17103026 0.78 DNM2 (0.60) DNM2S1PR2LMNASMN1; SMN2NPSR1
SCHEMBL8886910 0.78 DNM2 (0.60) DNM2S1PR2LMNASMN1; SMN2NPSR1
SCHEMBL31696305 0.75 CYP1A2 (0.41) DNM2LMNANPSR1
SCHEMBL24846616 0.74 DNM2 (0.59) DNM2LMNASMN1; SMN2HCAR3FLT3
SCHEMBL12228158 0.74 TLR8 (0.56) DNM2LMNASMN1; SMN2HCAR3FLT3
SCHEMBL15923413 0.73 DNM2 (0.55) DNM2S1PR2LMNASMN1; SMN2NPSR1
SCHEMBL15923128 0.73 DNM2 (0.55) DNM2S1PR2LMNASMN1; SMN2NPSR1
SCHEMBL9181933 0.72 DNM2 (0.54) DNM2NPSR1HCAR3FLT3TYRO3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1877481-B1 STABILISER COMPOSITION FOR HALIDE-CONTAINING POLYMERS SUN ACE KAKOH PTE LTD (SG) 2016-02-17 EP disclosed
US-7842743-B2 Stabiliser composition for halide-containing polymers SUN ACE KAKOH (PTE.) LTD. (SG) 2010-11-30 US disclosed
US-20090030123-A1 STABILISER COMPOSITION FOR HALIDE-CONTAINING POLYMERS SUN ACE KAKOH (PTE.) LTD. (SG) 2009-01-29 US disclosed
EP-1877481-A2 STABILISER COMPOSITION FOR HALIDE-CONTAINING POLYMERS Sun Ace Kakoh (Pte.) Ltd. (SG) 2008-01-16 EP disclosed
WO-2006110106-A1 STABILISER COMPOSITION FOR CHLORINE-CONTAINING POLYMERS SUN ACE KAKOK (PTE.) LTD. (SG) 2006-10-19 WO disclosed
WO-2006110112-A2 STABILISER COMPOSITION FOR HALIDE-CONTAINING POLYMERS SUN ACE KAKOH (PTE.) LTD. (SG) 2006-10-19 WO disclosed