Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 9/20 | 0.60 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.41 |
| ▸ | MERTK | Q12866 | 2/20 | 0.41 |
| ▸ | GAS6 | Q14393 | 2/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12963406 | 0.87 | DNM2 (0.43) | DNM2SMN1; SMN2CLK4KDM4ENPC1 | |
| SCHEMBL8346152 | 0.80 | CYP2C19 (0.44) | LMNASMN1; SMN2CLK4KDM4ENPC1 | |
| SCHEMBL3676779 | 0.78 | DNM2 (0.63) | DNM2SOAT1S1PR2LMNASMN1; SMN2 | |
| SCHEMBL8886903 | 0.77 | IDO1 (0.39) | DNM2SMN1; SMN2FLT3TYRO3MERTK | |
| SCHEMBL17103026 | 0.76 | DNM2 (0.60) | DNM2SOAT1S1PR2LMNASMN1; SMN2 | |
| SCHEMBL5665700 | 0.76 | DNM2 (0.60) | DNM2SOAT1S1PR2LMNASMN1; SMN2 | |
| SCHEMBL15923413 | 0.74 | DNM2 (0.55) | DNM2SOAT1S1PR2LMNASMN1; SMN2 | |
| SCHEMBL15923128 | 0.74 | DNM2 (0.55) | DNM2SOAT1S1PR2LMNASMN1; SMN2 | |
| SCHEMBL12933375 | 0.73 | HRH4 (0.50) | SMN1; SMN2KDM4ENPC1MAPTNFKB1 | |
| SCHEMBL12764505 | 0.72 | HRH4 (0.47) | SMN1; SMN2KDM4ENPC1MAPTNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668140-A | INSECTICIDE, ACARICIDE, NEMATOCIDE, FUNGICIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-16 | — | — | US | disclosed |