Hydrochloric Acid

Hydrochloric Acid

SCHEMBL593290

CCOC(=O)[C@@H](N)CO.Cl

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA known ✓ P10253 2/20 0.39
ALOX15 P16050 1/20 0.44
ALDH1A1 P00352 5/20 0.42
LMNA P02545 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SOAT1 P35610 1/20 0.39
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
PIN1 Q13526 1/20 0.37
CAD P27708 1/20 0.36
TRPA1 O75762 1/20 0.36
CYP1A2 P05177 1/20 0.35
CPB2 Q96IY4 1/20 0.35
HPGD P15428 2/20 0.33
METAP2 P50579 1/20 0.33
METAP1 P53582 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11223928 1.00 ALOX15 (0.44) ALOX15ALDH1A1LMNAHSD17B10GAA
Hydrochloric Acid SCHEMBL4534897 1.00 ALOX15 (0.44) ALOX15ALDH1A1LMNAHSD17B10GAA
Hydrochloric Acid SCHEMBL1553115 1.00 ALOX15 (0.44) ALOX15ALDH1A1LMNAHSD17B10GAA
Hydrochloric Acid SCHEMBL459507 1.00 ALOX15 (0.44) ALOX15ALDH1A1LMNAHSD17B10GAA
SCHEMBL366162 0.98
SCHEMBL818996 0.98
SCHEMBL367679 0.98
SCHEMBL31615213 0.95 ALOX15 (0.44) ALOX15ALDH1A1LMNAHSD17B10GAA
Water SCHEMBL5917424 0.95 ALOX15 (0.44) ALOX15ALDH1A1LMNAHSD17B10GAA
Hydrochloric Acid SCHEMBL16223251 0.93 ALOX15 (0.42) ALOX15ALDH1A1LMNAHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 336 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119899180-A Chiral oxazoline diester derivative and preparation method and application thereof 安徽农业大学 2025-04-29 CN claimed
CN-114853634-A Nicotinyl alcohol ether derivative, preparation method thereof, pharmaceutical composition and application 中国医学科学院药物研究所 2022-08-05 CN claimed
CN-102388017-A A method of synthesising an amino acid derivative of azelaic acid MALAYSIAN PALM OIL BOARD 2012-03-21 CN claimed
WO-2010117258-A1 A METHOD OF SYNTHESISING AN AMINO ACID DERIVATIVE OF AZELAIC ACID MALAYSIAN PALM OIL BOARD (MY) 2010-10-14 WO claimed
CN-100445273-C Calixarene aza-crown ether derivative, its preparation and use as metal ion fluorescent identification agent UNIV BEIJING NORMAL (CN) 2008-12-24 CN claimed
CN-1982300-A Calixarene aza-crown ether derivative, its preparation and use as metal ion fluorescent identification agent UNIV BEIJING NORMAL (CN) 2007-06-20 CN claimed
EP-1592715-A1 WATER SOLUBLE AND BIOCOMPATIBLE GELS OF HYALURONIC ACID CROSS-LINKED WITH BI-FUNCTIONAL L-AMINOACIDS OR L-AMINOESTERS Biosphere S.p.A. (IT) 2005-11-09 EP claimed
WO-2004067575-A1 WATER SOLUBLE AND BIOCOMPATIBLE GELS OF HYALURONIC ACID CROSS-LINKED WITH BI-FUNCTIONAL L-AMINOACIDS OR L-AMINOESTERS BIOSPHERE S.P.A. (IT) 2004-08-12 WO claimed
EP-4673451-A1 POLYMERIZABLE MONOMER Universität Linz (AT) 2026-01-07 EP disclosed
US-12492210-B2 Tricyclic compounds and their use HUTCHISON MEDIPHARMA LIMITED (CN) 2025-12-09 US disclosed
US-20250270184-A1 PROCESSES FOR THE PREPARATION OF FINERENONE ASSIA CHEMICAL INDUSTRIES LTD. (IL) 2025-08-28 US disclosed
EP-3338849-B1 BALLOON WRAPPING APPARATUS AND BALLOON WRAPPING METHOD TERUMO CORP (JP) 2025-06-25 EP disclosed
CN-120202243-A Thermosetting resin composition, cured film, substrate, and electronic component 捷恩智株式会社 2025-06-24 CN disclosed
WO-2025093456-A1 THIAZOLIDINE-4-CARBOXYLATE PROPERFUMES FIRMENICH SA (CH) 2025-05-08 WO disclosed
US-5122523-A Hypotensive agents BANYU PHARMACEUTICAL CO., LTD. (JP) 1992-06-16 US disclosed
EP-0153992-B1 WATER SOLUBLE DERIVATIVES OF 3,5-DIACETO AMIDO-2,4,6-TRIIODOBENZOIC ACID AND PROCESS FOR THEIR PREPARATION AND USE Dr. Franz Köhler Chemie GmbH (DE) 1991-10-16 EP disclosed
EP-0309766-A2 N-acylamino acid derivatives and their use BANYU PHARMACEUTICAL CO., LTD. (JP) 1989-04-05 EP disclosed
US-4607123-A X-RAY CONTRAST AGENTS DR. FRANZ KOHLER CHEMIE GMBH (DE) 1986-08-19 US disclosed
EP-0153992-A2 Water soluble derivatives of 3,5-diaceto amido-2,4,6-triiodobenzoic acid and process for their preparation and use Dr. Franz Köhler Chemie GmbH (DE) 1985-09-11 EP disclosed
US-4256748-A INOTROPIC AGENTS HOFFMANN-LA ROCHE INC. (US) 1981-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12492210-B2 Tricyclic compounds and their use CYP2C8, CYP11B2, CYP3A7 GAA 537/4885ALOX15 1414/4885ALDH1A1 1343/4885
US-20250270184-A1 PROCESSES FOR THE PREPARATION OF FINERENONE CYP11B1, CYP11B2, HSD17B7 GAA 2587/4885ALOX15 911/4885ALDH1A1 1664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.