Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 6/20 | 0.60 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.60 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.60 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.60 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.60 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.60 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.60 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.60 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.60 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CDC25A | P30304 | 3/20 | 0.51 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394692 | 0.84 | EPHA2 (0.53) | EPHA2GPBAR1AKR1B10AKR1B1EFNA1 | |
| SCHEMBL8332285 | 0.84 | GPBAR1 (0.66) | EPHA2GPBAR1AKR1B10AKR1B1EFNA1 | |
| SCHEMBL29100493 | 0.84 | GPBAR1 (0.66) | EPHA2GPBAR1AKR1B10AKR1B1EFNA1 | |
| SCHEMBL22068151 | 0.84 | GPBAR1 (0.66) | EPHA2GPBAR1AKR1B10AKR1B1EFNA1 | |
| SCHEMBL9176886 | 0.83 | GPBAR1 (0.66) | EPHA2GPBAR1AKR1B10AKR1B1EFNA1 | |
| SCHEMBL31747501 | 0.83 | GPBAR1 (0.65) | EPHA2GPBAR1AKR1B10AKR1B1EFNA1 | |
| SCHEMBL17912309 | 0.83 | EPHA2 (0.68) | EPHA2GPBAR1AKR1B10AKR1B1EFNA1 | |
| SCHEMBL3447578 | 0.83 | EPHA2 (0.68) | EPHA2GPBAR1AKR1B10AKR1B1EFNA1 | |
| SCHEMBL133953 | 0.83 | EPHA2 (0.68) | EPHA2GPBAR1AKR1B10AKR1B1EFNA1 | |
| SCHEMBL1163247 | 0.83 | EPHA2 (0.65) | EPHA2GPBAR1AKR1B10AKR1B1EFNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781599-B2 | economical; nontoxic; high yield; industrial scale; Grignard reaction; iron catalyst (FeCl3) and a diamine (ethylenediamine); cross-coupling of alkyl halide and aromatic organometallic; primary or secondary alkyl substituents; phenylcycloheptane from bromocycloheptane and phenyl magnesium bromide | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-08-24 | — | — | US | disclosed |
| US-20070123734-A1 | Process for production of aromatic compounds | JAPAN SCIENCE AND TECHNOLOGY AGENCY | 2007-05-31 | — | — | US | disclosed |
| EP-1724248-A1 | PROCESS FOR PRODUCTION OF AROMATIC COMPOUNDS | Japan Science and Technology Agency (JP) | 2006-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123734-A1 | Process for production of aromatic compounds | C9, C5, C1S | EPHA2 3538/4885GPBAR1 1785/4885AKR1B10 950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.