Styrene

Styrene

SCHEMBL3676912

C=CC=C.C=Cc1cccc(C=C)c1.C=Cc1ccccc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.70
TSHR P16473 1/20 0.70
TDP1 Q9NUW8 2/20 0.54
TP53 P04637 1/20 0.54
PTGS2 P35354 1/20 0.42
FAAH O00519 1/20 0.37
MAOB P27338 2/20 0.37
NFE2L2 Q16236 1/20 0.37
CYP19A1 P11511 1/20 0.37
MAOA P21397 1/20 0.37
CYP2A6 P11509 1/20 0.36
HDAC8 Q9BY41 2/20 0.36
LMNA P02545 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MCL1 Q07820 1/20 0.33
TRPA1 O75762 1/20 0.32
NOX1 Q9Y5S8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL9639895 0.95 ALDH1A1 (0.78) ALDH1A1TSHRTDP1TP53PTGS2
Styrene SCHEMBL9436827 0.89 ALDH1A1 (0.88) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL7703256 0.89 ALDH1A1 (0.88) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL1615767 0.89 ALDH1A1 (0.88) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL11097171 0.89 ALDH1A1 (0.88) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL7086204 0.89 ALDH1A1 (0.88) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL8351921 0.89 ALDH1A1 (0.88) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL7553099 0.89 ALDH1A1 (0.88) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL15179 0.89 ALDH1A1 (0.88) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL7632336 0.89 ALDH1A1 (0.88) ALDH1A1TSHRTDP1TP53MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754129-B2 Sealing system and process therefor ILLINOIS TOOL WORKS INC. (US) 2010-07-13 US disclosed
US-7390845-B2 Sealing system and process therefor ILLINOIS TOOL WORKS INC (US) 2008-06-24 US disclosed
US-20060172130-A1 Sealing system and process therefor ILLINOIS TOOL WORKS INC. 2006-08-03 US disclosed
EP-1534438-A2 SEALING SYSTEM AND PROCESS THEREFOR ILLINOIS TOOL WORKS INC. (US) 2005-06-01 EP disclosed
WO-2004011825-A2 SEALING SYSTEM AND PROCESS THEREFOR ILLINOIS TOOL WORKS INC. (US) 2004-02-05 WO disclosed
US-20040017051-A1 Sealing system and process therefor ILLINOIS TOOL WORKS INC. 2004-01-29 US disclosed