Styrene

Styrene

SCHEMBL9639895

C=Cc1cccc(C=C)c1.C=Cc1ccccc1

nearest known ligand 0.78

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.78
TSHR P16473 1/20 0.78
TDP1 Q9NUW8 2/20 0.58
TP53 P04637 1/20 0.58
PTGS2 P35354 1/20 0.44
MAOB P27338 2/20 0.39
NFE2L2 Q16236 2/20 0.39
CYP19A1 P11511 1/20 0.39
MAOA P21397 1/20 0.39
CYP2A6 P11509 1/20 0.39
HDAC8 Q9BY41 2/20 0.39
LMNA P02545 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
FAAH O00519 1/20 0.36
MCL1 Q07820 1/20 0.35
RELA Q04206 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL3676912 0.95 ALDH1A1 (0.70) ALDH1A1TSHRTDP1TP53PTGS2
Styrene SCHEMBL6455547 0.91
SCHEMBL21881 0.91 TDP1 (0.67) ALDH1A1TSHRTDP1TP53PTGS2
Water SCHEMBL20239051 0.88 TDP1 (0.64) ALDH1A1TSHRTDP1TP53PTGS2
SCHEMBL30381592 0.88 TDP1 (0.64) ALDH1A1TSHRTDP1TP53PTGS2
Ammonia Solution, Strong SCHEMBL31335086 0.88 TDP1 (0.64) ALDH1A1TSHRTDP1TP53PTGS2
Styrene SCHEMBL369036 0.88 ALDH1A1 (1.00) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL9776790 0.88 ALDH1A1 (1.00) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL11144289 0.88 ALDH1A1 (1.00) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL6258482 0.88 ALDH1A1 (1.00) ALDH1A1TSHRTDP1TP53MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2906330-A1 COATED ION EXCHANGE MEMBRANES Evoqua Water Technologies LLC (US) 2015-08-19 EP disclosed
EP-2903737-A1 HIGH-PERFORMANCE ANION EXCHANGE MEMBRANES AND METHODS OF MAKING SAME Evoqua Water Technologies LLC (US) 2015-08-12 EP disclosed
WO-2014055123-A1 HIGH-PERFORMANCE ANION EXCHANGE MEMBRANES AND METHODS OF MAKING SAME EVOQUA WATER TECHNOLOGIES LLC (US) 2014-04-10 WO disclosed
EP-0496513-A2 Process for producing ionexchange resins and use of the resins for separating amino acids BABCOCK-HITACHI KABUSHIKI KAISHA (JP) 1992-07-29 EP disclosed