SCHEMBL3676959

SCHEMBL3676959

c1ccc(-c2ccc(NC3CCCCC3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.49
NPC1 O15118 1/20 0.49
MAPT P10636 4/20 0.49
GAA P10253 2/20 0.49
LMNA P02545 2/20 0.49
POLB P06746 1/20 0.49
ADORA3 P0DMS8 1/20 0.48
PDE5A O76074 2/20 0.47
ACP1 P24666 2/20 0.47
MEN1 O00255 2/20 0.47
ALDH1A1 P00352 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 3/20 0.47
IDO1 P14902 1/20 0.46
EPHX1 P07099 2/20 0.45
HSD17B10 Q99714 2/20 0.45
APAF1 O14727 1/20 0.45
MAPK1 P28482 1/20 0.45
BLM P54132 1/20 0.45
TDP1 Q9NUW8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30800857 0.92 MAPT (0.55) RAB9ANPC1MAPTGAALMNA
SCHEMBL30800858 0.92 MAPT (0.55) RAB9ANPC1MAPTGAALMNA
SCHEMBL20419261 0.90 MEN1 (0.50) RAB9ANPC1MAPTGAALMNA
SCHEMBL1485904 0.87 KDM4E (0.53) RAB9ANPC1MAPTGAALMNA
SCHEMBL10480342 0.87 KDM4E (0.53) RAB9ANPC1MAPTGAALMNA
SCHEMBL24198978 0.87 KDM4E (0.53) RAB9ANPC1MAPTGAALMNA
SCHEMBL29594018 0.87 KDM4E (0.53) RAB9ANPC1MAPTGAALMNA
SCHEMBL24514268 0.87 KDM4E (0.53) RAB9ANPC1MAPTGAALMNA
SCHEMBL18639265 0.87 KDM4E (0.53) RAB9ANPC1MAPTGAALMNA
SCHEMBL285479 0.87 KDM4E (0.53) RAB9ANPC1MAPTGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3244464-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-02-23 EP disclosed
EP-1966225-B1 TRANSITION METAL COMPLEXES AND PREPARATION METHODS THEREOF LG CHEMICAL LTD (KR) 2013-12-25 EP disclosed
EP-1966223-B1 CATALYST COMPOSITION COMPRISING GROUP 4 TRANSITION METAL COMPLEXES AND METHOD FOR PREPARING POLYOLEFINS USING THE SAME LG CHEMICAL LTD (KR) 2013-08-14 EP disclosed
CN-102558245-A Catalyst composition comprising group 4 transition metal complexes and method for preparing polyolefins using the same LG CHEMICAL LTD 2012-07-11 CN disclosed
US-7807762-B2 Catalyst composition comprising Group 4 transition metal complexes and method for preparing polyolefins using the same LG CHEM, LTD. (KR) 2010-10-05 US disclosed
US-7678933-B2 Transition metal complexes and preparation methods thereof LG CHEM, LTD. (KR) 2010-03-16 US disclosed
US-20090030221-A1 Transition Metal Complexes and Preparation Methods Thereof LG CHEM, LTD (KR) 2009-01-29 US disclosed
US-20090005525-A1 Catalyst Composition Comprising Group 4 Transition Metal Complexes and Method for Preparing Polyolefins Using the Same LG CHEM , LTD. (KR) 2009-01-01 US disclosed
CN-101300261-A Catalyst composition comprising group 4 transition metal complexes and method for preparing polyolefins using the same LG CHEMICAL LTD (KR) 2008-11-05 CN disclosed
CN-101296932-A Transition metal complex and preparation method thereof LG CHEMICAL LTD (KR) 2008-10-29 CN disclosed
EP-1966223-A1 CATALYST COMPOSITION COMPRISING GROUP 4 TRANSITION METAL COMPLEXES AND METHOD FOR PREPARING POLYOLEFINS USING THE SAME LG Chem. Ltd. (KR) 2008-09-10 EP disclosed
EP-1966225-A1 TRANSITION METAL COMPLEXES AND PREPARATION METHODS THEREOF LG Chem, Ltd. (KR) 2008-09-10 EP disclosed
WO-2007078134-A1 TRANSITION METAL COMPLEXES AND PREPARATION METHODS THEREOF LG CHEM. LTD. (KR) 2007-07-12 WO disclosed
WO-2007078133-A1 CATALYST COMPOSITION COMPRISING GROUP 4 TRANSITION METAL COMPLEXES AND METHOD FOR PREPARING POLYOLEFINS USING THE SAME LG CHEM. LTD. (KR) 2007-07-12 WO disclosed
CN-1147489-C New bicyclo aminopyrazineone compound, its producing process and medical composition containing them ɪά��ʵ���� 2004-04-28 CN disclosed
CN-1277198-A New bicyclo aminopyrazineone compound, its producing process and medical composition containing them ADIR (FR) 2000-12-20 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090030221-A1 Transition Metal Complexes and Preparation Methods Thereof PICALM, TEC, PPIP5K2 RAB9A 2078/4885NPC1 2837/4885MAPT 1875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.