SCHEMBL367697

SCHEMBL367697

C=C(C(=O)O)c1ccccc1C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC5 P28715 1/20 0.53
FEN1 P39748 1/20 0.53
HPGD P15428 2/20 0.50
MYC P01106 1/20 0.46
ALDH1A1 P00352 2/20 0.45
KDM4E B2RXH2 1/20 0.45
HSD17B10 Q99714 1/20 0.45
KMT2A Q03164 2/20 0.44
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
HTT P42858 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
GAA P10253 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL30708075 0.86 ERCC5 (0.42) ERCC5FEN1HPGDMYCALDH1A1
SCHEMBL11123891 0.84 ALDH1A1 (0.52) ERCC5FEN1HPGDALDH1A1KDM4E
SCHEMBL9349886 0.83 HSD17B10 (0.47) ERCC5FEN1HPGDMYCALDH1A1
SCHEMBL24291982 0.82 MAOA (0.46) ERCC5FEN1HPGDMYCALDH1A1
SCHEMBL4622473 0.81 MAOA (0.46) ERCC5FEN1HPGDMYCALDH1A1
SCHEMBL8104638 0.79 ERCC5 (0.50) ERCC5FEN1HPGDMYCALDH1A1
SCHEMBL4804676 0.78 ALDH1A1 (0.42) HPGDALDH1A1KDM4EHSD17B10ALOX15
Rubidium SCHEMBL8119226 0.78 ERCC5 (0.49) ERCC5FEN1HPGDMYCALDH1A1
Toluic Acid SCHEMBL28076317 0.78 ALDH1A1 (0.50) ERCC5FEN1HPGDMYCALDH1A1
SCHEMBL1426459 0.78 NPC1 (0.46) ERCC5FEN1HPGDALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116855295-A Diesel engine oil composition and preparation method and application thereof 中国石油化工股份有限公司 2023-10-10 CN claimed
CN-106999629-B Low water content acrylate-acrylamide copolymers for ophthalmic devices 诺华股份有限公司 2020-02-21 CN claimed
CN-103965821-B A kind of sealant composition and display unit BOE TECHNOLOGY GROUP CO., LTD. (CN) 2016-03-16 CN claimed
CN-102633624-B Method for preparing methylcinnamic acid HUBEI YUANCHENG SAICHUANG TECHNOLOGY CO LTD 2015-07-08 CN claimed
CN-104487581-A Enzymes and methods for styrene synthesis PHYTOGENE INC 2015-04-01 CN claimed
CN-102654689-B Frame sealing glue, frame sealing glue photocuring method and liquid crystal display device BOE TECHNOLOGY GROUP CO LTD 2015-03-11 CN claimed
CN-103965821-A Frame sealant composition and display device BOE TECHNOLOGY GROUP CO LTD 2014-08-06 CN claimed
CN-103131567-A Hydroxide solid pipeline dredging maintenance agent and its preparation technology TIANJIN NANKAI DISTR REAL ESTATE CORP 2013-06-05 CN claimed
CN-102654689-A Frame sealing glue, frame sealing glue photocuring method and liquid crystal display device BOE TECHNOLOGY GROUP CO LTD 2012-09-05 CN claimed
CN-102633624-A Method for preparing methylcinnamic acid HUBEI YUANCHENG PHARMACEUTICAL 2012-08-15 CN claimed
CN-101965330-A Method for producing beta-mercapto carboxylic acids SHOWA DENKO KK 2011-02-02 CN claimed
CN-100534992-C Silybin esters derivatives and preparation and use thereof ZHEJIANG HISUN NATURELITE PHAR (CN) 2009-09-02 CN claimed
CN-1990484-A Silybin esters derivatives and preparation and use thereof ZHEJIANG HISUN NATURELITE PHAR (CN) 2007-07-04 CN claimed
CN-1270186-A Method for preparing curable composition and composition therefrom ROHM & HAAS (US) 2000-10-18 CN claimed
US-5821306-A POLYMER BLEND CONSISTING OF POLYPHENYLETHYL METHACRYLATE AND POLYPHENYLETHYL ACRYLATE PHARMACIA & UPJOHN GRONINGEN BV (NL) 1998-10-13 US claimed
EP-0784652-A1 INTRAOCULAR LENS MATERIALS Pharmacia & Upjohn Aktiebolag (SE) 1997-07-23 EP claimed
WO-1996011235-A1 INTRAOCULAR LENS MATERIALS PHARMACIA & UPJOHN AB (SE) 1996-04-18 WO claimed
EP-0327021-B1 COATING COMPOSITIONS FOR PREVENTING ADHESION OF AQUATIC ORGANISMS KANSAI PAINT CO. LTD. (JP) 1993-06-09 EP claimed
CN-116855295-A Diesel engine oil composition and preparation method and application thereof 中国石油化工股份有限公司 2023-10-10 CN disclosed
EP-0184201-A1 Rare earth phosphor and radiographic image conversion screen MITSUBISHI KASEI CORPORATION (JP) 1986-06-11 EP disclosed