Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.64 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.64 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367731 | 0.81 | L3MBTL1 (0.41) | KDM4EMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL366921 | 0.78 | KDM4E (1.00) | KDM4EMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL364293 | 0.76 | KMT2A (0.49) | KDM4EMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL367736 | 0.75 | KDM4E (0.70) | KDM4EMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL365009 | 0.73 | ALDH1A1 (0.62) | KDM4EMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL364999 | 0.73 | ALDH1A1 (0.60) | KDM4EMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL365639 | 0.73 | KMT2A (0.66) | KDM4EMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL365090 | 0.71 | ALDH1A1 (0.68) | KDM4EMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL364541 | 0.71 | KDM4E (1.00) | KDM4EMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL366557 | 0.70 | ALDH1A1 (0.48) | KDM4EMEN1KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |