SCHEMBL3677818

SCHEMBL3677818

N#CC(C(=O)OCCO)=C(c1ccccc1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
LMNA P02545 3/20 0.54
MAPK1 P28482 3/20 0.54
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.40
XBP1 P17861 1/20 0.40
RAB9A P51151 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TDP1 Q9NUW8 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.35
SLC7A5 Q01650 1/20 0.35
ESR1 P03372 1/20 0.35
RECQL P46063 1/20 0.34
HIF1A Q16665 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A3 Q01959 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32669188 0.89 LMNA (0.59) ALDH1A1LMNAMAPK1MAPTXBP1
SCHEMBL15797630 0.88 LMNA (0.57) ALDH1A1LMNAMAPK1MAPTXBP1
SCHEMBL11207543 0.86 ALDH1A1 (0.53) ALDH1A1LMNAMAPK1MAPTXBP1
SCHEMBL4743488 0.86 ALDH1A1 (0.63) ALDH1A1LMNAMAPK1GAAMAPT
SCHEMBL9717134 0.85 ALDH1A1 (0.52) ALDH1A1LMNAMAPK1MAPTXBP1
SCHEMBL11408376 0.85 ALDH1A1 (0.55) ALDH1A1LMNAMAPK1MAPTXBP1
SCHEMBL12253186 0.85 LMNA (0.55) ALDH1A1LMNAMAPK1MAPTXBP1
SCHEMBL502564 0.84 LMNA (0.67) ALDH1A1LMNAMAPK1RAB9ATDP1
Etocrylene SCHEMBL1768864 0.83 ALDH1A1 (0.62) ALDH1A1LMNAMAPK1GAAMAPT
SCHEMBL2141031 0.83 ALDH1A1 (0.55) ALDH1A1LMNAMAPK1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114533580-A Ultraviolet screening agent and preparation method and application thereof 水羊化妆品制造有限公司 2022-05-27 CN claimed
CN-114533580-A Ultraviolet screening agent and preparation method and application thereof 水羊化妆品制造有限公司 2022-05-27 CN disclosed
EP-2181151-B1 POLYCARBONATE COMPOSITIONS SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-03-16 EP disclosed
EP-2181151-B1 POLYCARBONATE COMPOSITIONS SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-03-16 EP disclosed
US-8759428-B2 Polycarbonate compositions SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-06-24 US disclosed
US-8759428-B2 Polycarbonate compositions SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-06-24 US disclosed
US-8759428-B2 Polycarbonate compositions SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-06-24 US disclosed
EP-2181151-A1 POLYCARBONATE COMPOSITIONS Sabic Innovative Plastics IP B.V. (NL) 2010-05-05 EP disclosed
WO-2009101016-A2 MODIFIED HYBRID NANOPARTICLES BASF SE (DE) 2009-08-20 WO disclosed
WO-2009026127-A1 POLYCARBONATE COMPOSITIONS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-02-26 WO disclosed
EP-0017703-A1 Copolymerizable (2-cyano-3,3-diarylacryloxy)alkylene compounds, a method of making them and the use of these compounds as ultraviolet light absorbers GAF CORPORATION (US) 1980-10-29 EP disclosed
US-4218392-A Two-step method of making copolymerizable, ultraviolet light absorber _2-cyano-3,3-diphenylacryloxy) alkylene acrylic acid esters GAF CORPORATION (US) 1980-08-19 US disclosed
US-4216267-A Flexible substrates containing a radiation curable coating composition GAF CORPORATION (US) 1980-08-05 US disclosed
US-4207253-A Method of making copolymerizable, ultraviolet light absorber (2-cyano-3,3-diphenylacryloxy) alkylene acrylic acid esters GAF CORPORATION (US) 1980-06-10 US disclosed
US-4202834-A Copolymerizable, ultraviolet light absorber (2-cyano-3,3-diphenylacryloxy) alkylene ethylenic ethers GAF CORPORATION (US) 1980-05-13 US disclosed
US-4178303-A (2-Cyano-3,3-diphenylacryloxy) alkylene acrylic acid esters GAF CORPORATION (US) 1979-12-11 US disclosed
EP-0003021-A1 Cyano-oligomer compositions and processes thereof GAF CORPORATION (US) 1979-07-25 EP disclosed
EP-0002676-A1 Radiation curable coating composition and a process for coating a substrate therewith GAF CORPORATION (US) 1979-07-11 EP disclosed
US-4129667-A Radiation curable coating composition comprising an acryl urethane oligomer and an ultra-violet absorber GAF CORPORATION (US) 1978-12-12 US disclosed
US-4128536-A ULTRAVIOLET LIGHT ABSORBERS GAF CORPORATION (US) 1978-12-05 US disclosed